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Ultra-thin membrane filter with a uniformly arrayed nanopore structure for nanoscale separation of extracellular vesicles without cake formation
DC Field | Value | Language |
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dc.date.accessioned | 2024-01-05T05:38:14Z | - |
dc.date.available | 2024-01-05T05:38:14Z | - |
dc.date.issued | 2023-01 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/197691 | - |
dc.description.abstract | Extracellular vesicles (EVs) have emerged as vehicles that mediate diverse cell-cell communication. However, in-depth understanding of these vesicles is hampered by a lack of a reliable isolation method to separate different types of EVs with high levels of integrity and purity. Here, we developed a nanoporous and ultra-thin membrane structure (NUTS) that warrants the size-based isolation of EVs without cake formation, minimizing the sample loss during the filtration process. By utilizing the micro-electro-mechanical systems (MEMS) technique, we could also control the pore size in nanoscale. We validated the performance of this membrane to separate EVs according to their size range. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | NANOSCALE ADVANCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Ultra-thin membrane filter with a uniformly arrayed nanopore structure for nanoscale separation of extracellular vesicles without cake formation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Others | - |
dc.contributor.googleauthor | Daesan Kim | - |
dc.contributor.googleauthor | Jaehyuk Lee | - |
dc.contributor.googleauthor | Boyoung Kim | - |
dc.contributor.googleauthor | Yujin Shin | - |
dc.contributor.googleauthor | Jinhong Park | - |
dc.contributor.googleauthor | Uijoo Kim | - |
dc.contributor.googleauthor | Minbaek Lee | - |
dc.contributor.googleauthor | Sang Bum Kim | - |
dc.contributor.googleauthor | Sunghoon Kim | - |
dc.identifier.doi | 10.1039/d2na00227b | - |
dc.identifier.pmid | 36756507 | - |
dc.citation.volume | 5 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 640 | - |
dc.citation.endPage | 649 | - |
dc.identifier.bibliographicCitation | NANOSCALE ADVANCES, Vol.5(3) : 640-649, 2023-01 | - |
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