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A Systematic Review and Meta-Analysis of Clinical Outcomes of Patients Undergoing Chronic Total Occlusion Percutaneous Coronary Intervention
DC Field | Value | Language |
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dc.contributor.author | 김병극 | - |
dc.date.accessioned | 2023-11-28T02:55:32Z | - |
dc.date.available | 2023-11-28T02:55:32Z | - |
dc.date.issued | 2022-11 | - |
dc.identifier.issn | 1042-3931 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/196690 | - |
dc.description.abstract | Objectives: Chronic total occlusion (CTO) percutaneous coronary intervention (PCI) can improve patient symptoms, but it remains controversial whether it impacts subsequent clinical outcomes. Methods: In this systematic review and meta-analysis, we queried PubMed, ScienceDirect, Cochrane Library, Web of Science, and Embase databases (last search: September 15, 2021). We investigated the impact of CTO-PCI on clinical events including all-cause mortality, cardiovascular death, myocardial infarction (MI), major adverse cardiovascular event (MACE), stroke, subsequent coronary artery bypass surgery, target-vessel revascularization, and heart failure hospitalizations. Pooled analysis was performed using a random-effects model. Results: A total of 58 publications with 54,540 patients were included in this analysis, of which 33 were observational studies of successful vs failed CTO-PCI, 19 were observational studies of CTO-PCI vs no CTO-PCI, and 6 were randomized controlled trials (RCTs). In observational studies, but not RCTs, CTO-PCI was associated with better clinical outcomes. Odds ratios (ORs) and 95% confidence intervals (CIs) for all-cause mortality, MACE, and MI were 0.52 (95% CI, 0.42-0.64), 0.46 (95% CI, 0.37-0.58), 0.66 (95% CI, 0.50-0.86), respectively for successful vs failed CTO-PCI studies; 0.38 (95% CI, 0.31-0.45), 0.57 (95% CI, 0.42-0.78), 0.65 (95% CI, 0.42-0.99), respectively, for observational studies of CTO-PCI vs no CTO-PCI; 0.72 (95% CI, 0.39-1.32), 0.69 (95% CI, 0.38-1.25), and 1.04 (95% CI, 0.46-2.37), respectively for RCTs. Conclusions: CTO-PCI is associated with better subsequent clinical outcomes in observational studies but not in RCTs. Appropriately powered RCTs are needed to conclusively determine the impact of CTO-PCI on clinical outcomes. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | HMP Communications | - |
dc.relation.isPartOf | JOURNAL OF INVASIVE CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Coronary Occlusion* / surgery | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Myocardial Infarction* / etiology | - |
dc.subject.MESH | Observational Studies as Topic | - |
dc.subject.MESH | Odds Ratio | - |
dc.subject.MESH | Percutaneous Coronary Intervention* / adverse effects | - |
dc.subject.MESH | Randomized Controlled Trials as Topic | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | A Systematic Review and Meta-Analysis of Clinical Outcomes of Patients Undergoing Chronic Total Occlusion Percutaneous Coronary Intervention | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Bahadir Simsek | - |
dc.contributor.googleauthor | Spyridon Kostantinis | - |
dc.contributor.googleauthor | Judit Karacsonyi | - |
dc.contributor.googleauthor | Khaldoon Alaswad | - |
dc.contributor.googleauthor | Michael Megaly | - |
dc.contributor.googleauthor | Dimitrios Karmpaliotis | - |
dc.contributor.googleauthor | Amirali Masoumi | - |
dc.contributor.googleauthor | Wissam A. Jaber | - |
dc.contributor.googleauthor | William Nicholson | - |
dc.contributor.googleauthor | Stephane Rinfret SM | - |
dc.contributor.googleauthor | Kambis Mashayekhi | - |
dc.contributor.googleauthor | Gerald S. Werner | - |
dc.contributor.googleauthor | Margaret McEntegart | - |
dc.contributor.googleauthor | Seung-Whan Lee | - |
dc.contributor.googleauthor | Jaikirshan J. Khatri | - |
dc.contributor.googleauthor | Scott A. Harding | - |
dc.contributor.googleauthor | Alexandre Avran | - |
dc.contributor.googleauthor | Farouc A. Jaffer | - |
dc.contributor.googleauthor | Darshan Doshi MS | - |
dc.contributor.googleauthor | Hsien-Li Kao | - |
dc.contributor.googleauthor | Georgios Sianos | - |
dc.contributor.googleauthor | Masahisa Yamane | - |
dc.contributor.googleauthor | Anastasios Milkas | - |
dc.contributor.googleauthor | Lorenzo Azzalini | - |
dc.contributor.googleauthor | Roberto Garbo | - |
dc.contributor.googleauthor | Khalid Tammam | - |
dc.contributor.googleauthor | Nidal Abi Rafeh | - |
dc.contributor.googleauthor | Ilias Nikolakopoulos | - |
dc.contributor.googleauthor | Evangelia Vemmou | - |
dc.contributor.googleauthor | Bavana V. Rangan BDS MPH | - |
dc.contributor.googleauthor | M. Nicholas Burke | - |
dc.contributor.googleauthor | Santiago Garcia | - |
dc.contributor.googleauthor | Kevin J. Croce | - |
dc.contributor.googleauthor | Eugene B. Wu | - |
dc.contributor.googleauthor | Etsuo Tsuchikane | - |
dc.contributor.googleauthor | Carlo Di Mario | - |
dc.contributor.googleauthor | Alfredo R. Galassi | - |
dc.contributor.googleauthor | Andrea Gagnor | - |
dc.contributor.googleauthor | Paul Knaapen | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.contributor.googleauthor | Byeong-Keuk Kim | - |
dc.contributor.googleauthor | Paul B. Poommipanit | - |
dc.contributor.googleauthor | Emmanouil S. Brilakis | - |
dc.contributor.localId | A00493 | - |
dc.relation.journalcode | J01467 | - |
dc.identifier.eissn | 1557-2501 | - |
dc.identifier.pmid | 36227013 | - |
dc.identifier.url | https://www.hmpgloballearningnetwork.com/site/jic/original-research/systematic-review-and-meta-analysis-clinical-outcomes-patients | - |
dc.subject.keyword | percutaneous coronary intervention | - |
dc.subject.keyword | systematic review | - |
dc.subject.keyword | chronic total occlusion | - |
dc.subject.keyword | clinical outcomes | - |
dc.subject.keyword | meta-analysis | - |
dc.contributor.alternativeName | Kim, Byeong Keuk | - |
dc.contributor.affiliatedAuthor | 김병극 | - |
dc.citation.volume | 34 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | E763 | - |
dc.citation.endPage | E775 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INVASIVE CARDIOLOGY, Vol.34(11) : E763-E775, 2022-11 | - |
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