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Resting-state prefrontal EEG biomarker in correlation with postoperative delirium in elderly patients
DC Field | Value | Language |
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dc.contributor.author | 구본녀 | - |
dc.contributor.author | 김긍년 | - |
dc.contributor.author | 김정민 | - |
dc.contributor.author | 박수정 | - |
dc.contributor.author | 이기영 | - |
dc.contributor.author | 하윤 | - |
dc.date.accessioned | 2023-11-07T07:44:48Z | - |
dc.date.available | 2023-11-07T07:44:48Z | - |
dc.date.issued | 2023-09 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/196508 | - |
dc.description.abstract | Postoperative delirium (POD) is associated with adverse outcomes in elderly patients after surgery. Electroencephalography (EEG) can be used to develop a potential biomarker for degenerative cerebral dysfunctions, including mild cognitive impairment and dementia. This study aimed to explore the relationship between preoperative EEG and POD. We included 257 patients aged >70 years who underwent spinal surgery. We measured the median dominant frequency (MDF), which is a resting-state EEG biomarker involving intrinsic alpha oscillations that reflect an idle cortical state, from the prefrontal regions. Additionally, the mini-mental state examination and Montreal cognitive assessment (MoCA) were performed before surgery as well as 5 days after surgery. For long-term cognitive function follow up, the telephone interview for cognitive status™ (TICS) was performed 1 month and 1 year after surgery. Fifty-two (20.2%) patients were diagnosed with POD. A multivariable logistic regression analysis that included age, MoCA score, Charlson comorbidity index score, Mini Nutritional Assessment, and the MDF as variables revealed that the MDF had a significant odds ratio of 0.48 (95% confidence interval 0.27-0.85). Among the patients with POD, the postoperative neurocognitive disorders could last up to 1 year. Low MDF on preoperative EEG was associated with POD in elderly patients undergoing surgery. EEG could be a novel potential tool for identifying patients at a high risk of POD. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Frontiers Research Foundation | - |
dc.relation.isPartOf | FRONTIERS IN AGING NEUROSCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Resting-state prefrontal EEG biomarker in correlation with postoperative delirium in elderly patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Jeongmin Kim | - |
dc.contributor.googleauthor | Sujung Park | - |
dc.contributor.googleauthor | Keung-Nyun Kim | - |
dc.contributor.googleauthor | Yoon Ha | - |
dc.contributor.googleauthor | Sang-Jun Shin | - |
dc.contributor.googleauthor | Wonseok Cha | - |
dc.contributor.googleauthor | Ki-Young Lee | - |
dc.contributor.googleauthor | Jungmi Choi | - |
dc.contributor.googleauthor | Bon-Nyeo Koo | - |
dc.identifier.doi | 10.3389/fnagi.2023.1224264 | - |
dc.contributor.localId | A00193 | - |
dc.contributor.localId | A00331 | - |
dc.contributor.localId | A00884 | - |
dc.contributor.localId | A05707 | - |
dc.contributor.localId | A02695 | - |
dc.contributor.localId | A04255 | - |
dc.relation.journalcode | J00908 | - |
dc.identifier.eissn | 1663-4365 | - |
dc.identifier.pmid | 37818480 | - |
dc.subject.keyword | elderly | - |
dc.subject.keyword | electroencephalography | - |
dc.subject.keyword | median dominant frequency | - |
dc.subject.keyword | postoperative complications | - |
dc.subject.keyword | postoperative delirium | - |
dc.contributor.alternativeName | Ku, Bon Nyo | - |
dc.contributor.affiliatedAuthor | 구본녀 | - |
dc.contributor.affiliatedAuthor | 김긍년 | - |
dc.contributor.affiliatedAuthor | 김정민 | - |
dc.contributor.affiliatedAuthor | 박수정 | - |
dc.contributor.affiliatedAuthor | 이기영 | - |
dc.contributor.affiliatedAuthor | 하윤 | - |
dc.citation.volume | 15 | - |
dc.citation.startPage | 1224264 | - |
dc.identifier.bibliographicCitation | FRONTIERS IN AGING NEUROSCIENCE, Vol.15 : 1224264, 2023-09 | - |
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