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Role of diagnostic laparoscopy in deciding primary treatment in advanced-stage ovarian cancer
DC Field | Value | Language |
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dc.contributor.author | 김상운 | - |
dc.contributor.author | 김성훈 | - |
dc.contributor.author | 김영태 | - |
dc.contributor.author | 남은지 | - |
dc.contributor.author | 이용재 | - |
dc.contributor.author | 이정윤 | - |
dc.date.accessioned | 2023-08-09T07:07:01Z | - |
dc.date.available | 2023-08-09T07:07:01Z | - |
dc.date.issued | 2023-03 | - |
dc.identifier.issn | 2005-0380 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/196058 | - |
dc.description.abstract | Objective: We evaluated the usefulness of preoperative diagnostic laparoscopy for treatmentplanning in patients with advanced-stage ovarian cancer. Methods: We retrospectively analyzed 614 patients diagnosed with advanced-stage ovariancancer between Januar y 2010 and May 2018. Primar y debulking surger y (PDS) or neoadjuvantchemotherapy (NAC) followed by inter val debulking surger y were selected based onpreoperative laparoscopic (Group 1, n=192) and computed tomography findings (Group 2,n=422). The primar y outcomes in the PDS and NAC groups were suboptimal cytoreduction(residual disease >1 cm) rate and non-high-grade serous carcinoma (non-HGSC) rate,respectively. Results: The patients who under went PDS in group 1 and group 2 were 49 (25.5%) and 279(66.1%), respectively. The suboptimal cytoreduction rate after PDS was lower in Group 1than in Group 2 (2.0% vs 11.1%, p=0.023). Moreover, Group 1 showed a tendency toward alower proportion of non-HGSC patients who under went NAC than that in Group 2 (9.1%vs. 15.4%, p=0.069). Further, Group 1 showed lower rates of postoperative morbidity thanGroup 2 (5.2% vs. 10.4%, p=0.033). However, Kaplan–Meier analysis showed no significantdifferences in sur vival outcomes between the 2 groups. Conclusion: Diagnostic laparoscopy reduced the suboptimal cytoreduction rate in the PDSgroup and the implementation rate of NAC in non-HGSC patients. Moreover, it reducedpostoperative morbidity without affecting sur vival in both groups. Thus, diagnosticlaparoscopy is a valuable diagnostic tool for determining the primar y treatment. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Asian Society of Gynecologic Oncology : Taehan Puin Chongyang Hakhoe | - |
dc.relation.isPartOf | JOURNAL OF GYNECOLOGIC ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Carcinoma, Ovarian Epithelial / drug therapy | - |
dc.subject.MESH | Chemotherapy, Adjuvant | - |
dc.subject.MESH | Cytoreduction Surgical Procedures / methods | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Laparoscopy* | - |
dc.subject.MESH | Neoadjuvant Therapy | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Ovarian Neoplasms* / diagnosis | - |
dc.subject.MESH | Ovarian Neoplasms* / drug therapy | - |
dc.subject.MESH | Ovarian Neoplasms* / surgery | - |
dc.subject.MESH | Retrospective Studies | - |
dc.title | Role of diagnostic laparoscopy in deciding primary treatment in advanced-stage ovarian cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Obstetrics and Gynecology (산부인과학교실) | - |
dc.contributor.googleauthor | Yong Jae Lee | - |
dc.contributor.googleauthor | Young Shin Chung | - |
dc.contributor.googleauthor | Jung-Yun Lee | - |
dc.contributor.googleauthor | Eun Ji Nam | - |
dc.contributor.googleauthor | Sang Wun Kim | - |
dc.contributor.googleauthor | Young Tae Kim | - |
dc.contributor.googleauthor | Sunghoon Kim | - |
dc.identifier.doi | 10.3802/jgo.2023.34.e17 | - |
dc.contributor.localId | A00526 | - |
dc.contributor.localId | A00595 | - |
dc.contributor.localId | A00729 | - |
dc.contributor.localId | A01262 | - |
dc.contributor.localId | A05165 | - |
dc.contributor.localId | A04638 | - |
dc.relation.journalcode | J01428 | - |
dc.identifier.eissn | 2005-0399 | - |
dc.identifier.pmid | 36562129 | - |
dc.subject.keyword | Cytoreductive Surgery | - |
dc.subject.keyword | Neoadjuvant Chemotherapy | - |
dc.subject.keyword | Ovarian Cancer | - |
dc.subject.keyword | Surgical Diagnostic Technique | - |
dc.contributor.alternativeName | Kim, Sang Wun | - |
dc.contributor.affiliatedAuthor | 김상운 | - |
dc.contributor.affiliatedAuthor | 김성훈 | - |
dc.contributor.affiliatedAuthor | 김영태 | - |
dc.contributor.affiliatedAuthor | 남은지 | - |
dc.contributor.affiliatedAuthor | 이용재 | - |
dc.contributor.affiliatedAuthor | 이정윤 | - |
dc.citation.volume | 34 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | e17 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GYNECOLOGIC ONCOLOGY, Vol.34(2) : e17, 2023-03 | - |
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