Cited 17 times in
New-onset neurodegenerative diseases as long-term sequelae of SARS-CoV-2 infection: A systematic review and meta-analysis
DC Field | Value | Language |
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dc.contributor.author | 김용욱 | - |
dc.contributor.author | 신재일 | - |
dc.contributor.author | 박종미 | - |
dc.date.accessioned | 2023-07-25T04:57:41Z | - |
dc.date.available | 2023-07-25T04:57:41Z | - |
dc.date.issued | 2023-07 | - |
dc.identifier.issn | 0146-6615 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195594 | - |
dc.description.abstract | The association between SARS-CoV-2 infection with increased risk for new-onset neurodegenerative diseases remains unclear. Therefore, this meta-analysis aims to elucidate whether new-onset neurodegenerative diseases are long-term sequelae of SARS-CoV-2 infection. PubMed/MEDLINE, CENTRAL, and EMBASE were systematically searched for articles published up to January 10, 2023. A systematic review and meta-analysis were performed to calculate the pooled effect size, expressed as hazard ratios (HR) with corresponding 95% confidence interval (CI) of each outcome. Twelve studies involving 33 146 809 individuals (2 688 417 post-COVID-19 cases and 30 458 392 controls) were included in the present meta-analysis. The pooled analyses compared with control groups showed a significant association between SARS-CoV-2 infection and increased risk for new-onset Alzheimer's disease (HR = 1.50, 95% CI 1.22-1.85, I2 = 97%), dementia (HR = 1.66, 95% CI 1.42-1.94, I2 = 91%), and Parkinson's disease (HR = 1.44, 95% CI 1.06-1.95, I2 = 86%) among COVID-19 survivors. SARS-CoV-2 infection may be associated with a higher risk for new-onset neurodegenerative diseases in recovered COVID-19 patients. Future studies are warranted to determine the biological mechanisms underlying the neurodegenerative consequences of COVID-19 as long-term sequelae of SARS-CoV-2 infection. © 2023 Wiley Periodicals LLC. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley-Liss | - |
dc.relation.isPartOf | JOURNAL OF MEDICAL VIROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Alzheimer Disease* | - |
dc.subject.MESH | COVID-19* / complications | - |
dc.subject.MESH | Disease Progression | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Neurodegenerative Diseases* / epidemiology | - |
dc.subject.MESH | Neurodegenerative Diseases* / etiology | - |
dc.subject.MESH | SARS-CoV-2 | - |
dc.title | New-onset neurodegenerative diseases as long-term sequelae of SARS-CoV-2 infection: A systematic review and meta-analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Rehabilitation Medicine (재활의학교실) | - |
dc.contributor.googleauthor | Masoud Rahmati | - |
dc.contributor.googleauthor | Dong Keon Yon | - |
dc.contributor.googleauthor | Seung Won Lee | - |
dc.contributor.googleauthor | Pinar Soysal | - |
dc.contributor.googleauthor | Ai Koyanagi | - |
dc.contributor.googleauthor | Louis Jacob | - |
dc.contributor.googleauthor | Yusheng Li | - |
dc.contributor.googleauthor | Jong Mi Park | - |
dc.contributor.googleauthor | Yong Wook Kim | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.contributor.googleauthor | Lee Smith | - |
dc.identifier.doi | 10.1002/jmv.28909 | - |
dc.contributor.localId | A00750 | - |
dc.contributor.localId | A02142 | - |
dc.relation.journalcode | J01587 | - |
dc.identifier.eissn | 1096-9071 | - |
dc.identifier.pmid | 37394783 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/jmv.28909 | - |
dc.subject.keyword | COVID-19 | - |
dc.subject.keyword | SARS-CoV-2 | - |
dc.subject.keyword | meta-analysis | - |
dc.subject.keyword | neurodegenerative disorders | - |
dc.contributor.alternativeName | Kim, Yong Wook | - |
dc.contributor.affiliatedAuthor | 김용욱 | - |
dc.contributor.affiliatedAuthor | 신재일 | - |
dc.citation.volume | 95 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | e28909 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MEDICAL VIROLOGY, Vol.95(7) : e28909, 2023-07 | - |
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