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The Epidemiological and Clinical Characteristics of the Largest Outbreak of Enterohemorrhagic Escherichia coli in Korea
DC Field | Value | Language |
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dc.contributor.author | 김용찬 | - |
dc.contributor.author | 박윤수 | - |
dc.contributor.author | 허석재 | - |
dc.contributor.author | 허남우 | - |
dc.date.accessioned | 2023-07-12T02:28:19Z | - |
dc.date.available | 2023-07-12T02:28:19Z | - |
dc.date.issued | 2023-04 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195321 | - |
dc.description.abstract | Background: The largest outbreak of enterohemorrhagic Escherichia coli (EHEC) O157:H7 occurred at a preschool in South Korea from June 12 to 29, 2020. This study aimed to analyze the epidemiological and clinical characteristics of EHEC infection in this outbreak. Methods: Epidemiological investigation was performed on all 184 children and 19 workers at the preschool using a standard questionnaire to assess symptoms, food intake, attendance, and special activity history. Pulsed-field gel electrophoresis analysis of confirmed cases was performed to determine genetic relevance. Results: During this outbreak, 103 children were affected, whereas only one infection was identified in adults. Of the 103 pediatric patients, 85 had symptoms (82.5%), including diarrhea, abdominal pain, bloody stool, fever, and vomiting. Thirty-two patients (31.1%) were hospitalized, 15 (14.6%) were diagnosed with hemolytic uremic syndrome, and 4 (3.9%) received dialysis treatment. Pulsed-field gel electrophoresis analysis identified 4 genotypes with high genetic relevance (92.3%). Epidemiological investigation revealed that this outbreak might have occurred from ingesting foods stored in a refrigerator with a constant temperature above 10°C, which was conducive to bacterial growth. Despite several measures after outbreak recognition, new infections continued to appear. Therefore, the preschool was forced to close on June 19 to prevent further person-to-person transmission. Conclusion: Our findings from the response to the largest outbreak will help prepare countermeasures against future EHEC outbreak. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | 대한의학회(The Korean Academy of Medical Sciences) | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Diarrhea / epidemiology | - |
dc.subject.MESH | Disease Outbreaks | - |
dc.subject.MESH | Enterohemorrhagic Escherichia coli* / genetics | - |
dc.subject.MESH | Escherichia coli Infections* / diagnosis | - |
dc.subject.MESH | Escherichia coli Infections* / epidemiology | - |
dc.subject.MESH | Escherichia coli Infections* / microbiology | - |
dc.subject.MESH | Escherichia coli O157* / genetics | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.title | The Epidemiological and Clinical Characteristics of the Largest Outbreak of Enterohemorrhagic Escherichia coli in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Namwoo Heo | - |
dc.contributor.googleauthor | Jihee Lee | - |
dc.contributor.googleauthor | Yeonkyung Kim | - |
dc.contributor.googleauthor | Donghan Lee | - |
dc.contributor.googleauthor | Seok-Jae Heo | - |
dc.contributor.googleauthor | Yoon Soo Park | - |
dc.contributor.googleauthor | Jae-Won Yun | - |
dc.contributor.googleauthor | Yong Chan Kim | - |
dc.identifier.doi | 10.3346/jkms.2023.38.e117 | - |
dc.contributor.localId | A00752 | - |
dc.contributor.localId | A01598 | - |
dc.relation.journalcode | J01517 | - |
dc.identifier.eissn | 1598-6357 | - |
dc.identifier.pmid | 37069811 | - |
dc.subject.keyword | Children | - |
dc.subject.keyword | EHEC | - |
dc.subject.keyword | Epidemiological Investigation | - |
dc.subject.keyword | Food Poisoning | - |
dc.subject.keyword | Gyeonggi-do | - |
dc.subject.keyword | Korea | - |
dc.subject.keyword | Outbreak | - |
dc.subject.keyword | Transmission | - |
dc.contributor.alternativeName | Kim, Yong Chan | - |
dc.contributor.affiliatedAuthor | 김용찬 | - |
dc.contributor.affiliatedAuthor | 박윤수 | - |
dc.citation.volume | 38 | - |
dc.citation.number | 15 | - |
dc.citation.startPage | e117 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.38(15) : e117, 2023-04 | - |
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