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Evaluation and analysis of radiation exposure to normal tissues during gamma knife radiosurgery for vestibular schwannoma
DC Field | Value | Language |
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dc.date.accessioned | 2023-06-02T00:53:30Z | - |
dc.date.available | 2023-06-02T00:53:30Z | - |
dc.date.issued | 2022-07 | - |
dc.identifier.issn | 2322-3243 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/194496 | - |
dc.description.abstract | Background: A follow-up study of gamma knife radiosurgery has shown that postoperative radiation necrosis, radiation-induced edema, and malignant metastasis may occur. This may be due to secondary radiation exposure, therefore, it becomes necessary to actively reduce exposure to normal organs. Materials and Methods: In this study, the secondary radiation dose to the surrounding normal organs was measured during gamma-knife radiosurgery for vestibular schwannoma disease. Using a human pediatric phantom and a glass dosimeter, a treatment plan was established according to the tumor volume, and then the exposure dose to important normal organs in both eyes, thyroid gland, sternum, and both lungs was measured. Results: According to this study, the cancer occurrence probability due to secondary exposure was calculated to be 7 cases per 100,000 people up to the case of the eye and thyroid gland. Exposure doses of 100.2±0.79 mGy or more were measured in both eyes, which is approximately 1000 times that of a chest X-ray or a flight from Seoul to New York. This indicates exposure through gamma knife surgery. The dose to the thyroid gland was 12.7±0.05 mGy, which exceeds the effective dose of 10 mSv in abdominal computed tomography. Conclusion: By measuring the secondary exposure dose to normal organs during gamma-knife surgery for vestibular schwannoma disease, it was confirmed that the eyes and thyroid gland were exposed dangerously. Therefore, for pediatric patients specifically, a treatment plan that actively reduces secondary exposure is required. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Baresh-e-Danesh Press | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF RADIATION RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Evaluation and analysis of radiation exposure to normal tissues during gamma knife radiosurgery for vestibular schwannoma | - |
dc.type | Article | - |
dc.contributor.college | Others | - |
dc.contributor.department | Severance Hospital (세브란스병원) | - |
dc.contributor.googleauthor | J.A. Lee | - |
dc.contributor.googleauthor | S.R. Kim | - |
dc.contributor.googleauthor | S.H. Yoon | - |
dc.contributor.googleauthor | J.S. Kim | - |
dc.contributor.googleauthor | H.J. Yang | - |
dc.contributor.googleauthor | G.H. Kim | - |
dc.identifier.doi | 10.52547/ijrr.20.3.8 | - |
dc.relation.journalcode | J03457 | - |
dc.identifier.eissn | 2345-4229 | - |
dc.subject.keyword | Gamma knife radiosurgery | - |
dc.subject.keyword | secondary radiation exposure | - |
dc.subject.keyword | secondary cancer | - |
dc.subject.keyword | Vestibular schwannoma | - |
dc.citation.volume | 20 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 571 | - |
dc.citation.endPage | 578 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF RADIATION RESEARCH, Vol.20(3) : 571-578, 2022-07 | - |
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