Cited 0 times in
약물유전자검사 결과 해석의 임상검사실 적용 권고안
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임정훈 | - |
dc.date.accessioned | 2023-04-07T01:13:54Z | - |
dc.date.available | 2023-04-07T01:13:54Z | - |
dc.date.issued | 2022-08 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193830 | - |
dc.description.abstract | As various clinical genetic tests become widely available, the quality of clinical practice in several medical fields, including clinical pharmacogenetics, can be dramatically improved based on genetic test results. Importantly, standardization and the appropriate result interpretation of pharmacogenetic tests are crucial steps toward successful clinical implementation. Among various guidelines published to support accurate clinical decisions, the most commonly utilized evidence is systematically organized in the Clinical Pharmacogenetics Implementation Consortium guidelines, which are regularly updated. The establishment of accurate evidence for each drug-gene pair in pharmacogenetic test result interpretation is essential, but is a complicated and challenging issue. Herein, we provide up-to-date evidence for preparing professional interpretative comments in clinical pharmacogenetic test reports. We provide therapeutic recommendations based on pharmacological genotype-phenotype annotations for a total of 32 drug-gene pairs with sufficient clinical evidence. This document aims to provide reliable evidence and practical information for pharmacogenetic variant interpretation in routine clinical settings, to maximize the efficacy and minimize the side-effects of various pharmacotherapies. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | Korean Society for Laboratory Medicine | - |
dc.relation.isPartOf | Laboratory Medicine Online | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 약물유전자검사 결과 해석의 임상검사실 적용 권고안 | - |
dc.title.alternative | Recommendations for Clinical Application of Pharmacogenetic Test Results Interpretation by Clinical Laboratories | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | 임정훈 | - |
dc.contributor.googleauthor | 김지은 | - |
dc.contributor.googleauthor | 조선미 | - |
dc.identifier.doi | 10.47429/lmo.2022.12.4.244 | - |
dc.contributor.localId | A04654 | - |
dc.relation.journalcode | J02151 | - |
dc.identifier.eissn | 2093-6338 | - |
dc.subject.keyword | Pharmacogenetics | - |
dc.subject.keyword | Pharmacogenomic variants | - |
dc.subject.keyword | Practice guideline | - |
dc.contributor.alternativeName | Rim, John Hoon | - |
dc.contributor.affiliatedAuthor | 임정훈 | - |
dc.citation.volume | 12 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 244 | - |
dc.citation.endPage | 261 | - |
dc.identifier.bibliographicCitation | Laboratory Medicine Online, Vol.12(4) : 244-261, 2022-08 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.