Cited 5 times in
Cardiovascular Outcomes according to Comorbidities and Low-Density Lipoprotein Cholesterol in Korean People with Type 2 Diabetes Mellitus
DC Field | Value | Language |
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dc.contributor.author | 김현창 | - |
dc.date.accessioned | 2023-03-27T02:43:42Z | - |
dc.date.available | 2023-03-27T02:43:42Z | - |
dc.date.issued | 2023-01 | - |
dc.identifier.issn | 2233-6079 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193682 | - |
dc.description.abstract | Background: There are no clear data to support the cardiovascular (CV) risk categories and low-density lipoprotein cholesterol (LDL-C) treatment goals in Korean people with type 2 diabetes mellitus (T2DM). We evaluated the incidence of cardiovascular disease (CVD) according to comorbidities and suggested LDL-C treatment goals in Korean people with T2DM in nationwide cohort data. Methods: Using the Korean National Health Insurance Service database, 248,002 people aged 30 to 90 years with T2DM who underwent routine health check-ups during 2009 were included. Subjects with previous CVD were excluded from the study. The primary outcome was incident CVD, defined as a composite of myocardial infarction and ischemic stroke during the follow-up period from 2009 to 2018. Results: The mean age of the study participants was 59.6±10.9 years, and median follow-up period was 9.3 years. CVD incidence increased in the order of DM duration of 5 years or more (12.04/1,000 person-years), hypertension (HT) (12.27/1,000 personyears), three or more CV risk factors (14.10/1,000 person-years), and chronic kidney disease (18.28/1,000 person-years). The risk of incident CVD increased linearly from an LDL-C level of ≥70 mg/dL in most patients with T2DM. In T2DM patients without HT or with a DM duration of less than 5 years, the CVD incidence increased from LDL-C level of ≥100 mg/dL. Conclusion: For primary prevention of CVD in Korean adults with T2DM, it can be helpful to lower LDL-C targets when there are chronic kidney disease, HT, a long duration of diabetes mellitus, or three or more CV risk factors. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Diabetes Association | - |
dc.relation.isPartOf | DIABETES & METABOLISM JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Cardiovascular Diseases* / epidemiology | - |
dc.subject.MESH | Cardiovascular Diseases* / prevention & control | - |
dc.subject.MESH | Cholesterol, LDL | - |
dc.subject.MESH | Diabetes Mellitus, Type 2* / complications | - |
dc.subject.MESH | Diabetes Mellitus, Type 2* / epidemiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension* / complications | - |
dc.subject.MESH | Hypertension* / epidemiology | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Cardiovascular Outcomes according to Comorbidities and Low-Density Lipoprotein Cholesterol in Korean People with Type 2 Diabetes Mellitus | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine (예방의학교실) | - |
dc.contributor.googleauthor | Min Kyong Moon | - |
dc.contributor.googleauthor | Junghyun Noh | - |
dc.contributor.googleauthor | Eun-Jung Rhee | - |
dc.contributor.googleauthor | Sang Hyun Park | - |
dc.contributor.googleauthor | Hyeon Chang Kim | - |
dc.contributor.googleauthor | Byung Jin Kim | - |
dc.contributor.googleauthor | Hae Jin Kim | - |
dc.contributor.googleauthor | Seonghoon Choi | - |
dc.contributor.googleauthor | Jin Oh Na | - |
dc.contributor.googleauthor | Young Youl Hyun | - |
dc.contributor.googleauthor | Bum Joon Kim | - |
dc.contributor.googleauthor | Kyung-Do Han | - |
dc.contributor.googleauthor | In-Kyung Jeong | - |
dc.identifier.doi | 10.4093/dmj.2021.0344 | - |
dc.contributor.localId | A01142 | - |
dc.relation.journalcode | J00720 | - |
dc.identifier.eissn | 2233-6087 | - |
dc.identifier.pmid | 36727163 | - |
dc.subject.keyword | Cardiovascular diseases | - |
dc.subject.keyword | Cholesterol | - |
dc.subject.keyword | Diabetes mellitus | - |
dc.subject.keyword | Dyslipidemias | - |
dc.subject.keyword | Korea | - |
dc.contributor.alternativeName | Kim, Hyeon Chang | - |
dc.contributor.affiliatedAuthor | 김현창 | - |
dc.citation.volume | 47 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 45 | - |
dc.citation.endPage | 58 | - |
dc.identifier.bibliographicCitation | DIABETES & METABOLISM JOURNAL, Vol.47(1) : 45-58, 2023-01 | - |
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