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Influence of Handgrip Strength and Psoas Muscle Index on Analgesic Efficacy of Epidural Steroid Injection in Patients With Degenerative Lumbar Spinal Disease
DC Field | Value | Language |
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dc.contributor.author | 김희정 | - |
dc.contributor.author | 박상준 | - |
dc.contributor.author | 윤경봉 | - |
dc.contributor.author | 김신형 | - |
dc.contributor.author | 전은경 | - |
dc.date.accessioned | 2022-12-22T04:55:31Z | - |
dc.date.available | 2022-12-22T04:55:31Z | - |
dc.date.issued | 2022-10 | - |
dc.identifier.issn | 1533-3159 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/192253 | - |
dc.description.abstract | Background: Handgrip strength (HGS) and psoas muscle index (PMI) are widely used protocols for screening or diagnosing sarcopenia by measuring muscle strength and mass. Epidural steroid injection (ESI) is a common intervention for the treatment of spinal pain; however, the influence of pre-procedural sarcopenic status on therapeutic effects after ESI has not been investigated. Objectives: In the present study, whether pre-procedural HGS or PMI predicts analgesic efficacy of ESI in elderly patients with degenerative lumbar spinal disease was investigated. Study design: This was a retrospective observational study. Setting: The study included patients from the outpatient department for interventional pain management at a university hospital. Methods: Following institutional review board (IRB) approval, patients >= 65 years of age who underwent fluoroscopy-guided lumbar ESI from 2016 to 2017 in our clinic were enrolled in the present study. Good analgesia was defined as >= 50% reduction in pain score at 4 weeks after injection. Patient characteristics, pain-related factors, clinical factors, HGS, and PMI measurements were collected and analyzed using multivariate analysis to identify the predictors of good analgesia after lumbar ESI. In addition, a receiver operating characteristic curve (ROC) analysis was performed, and area under the curve (AUC) values with 95% confidence interval (CI) were calculated for the HGS. Results: A total of 259 patients satisfied the study protocol requirements. HGS was significantly higher in the good analgesia group (23.12 ± 7.54 vs 16.55 ± 6.66 kg, P < 0.001). However, the PMI did not differ between the 2 groups (5.25 ± 1.55 vs 5.08 ± 1.69 cm2/m2, P = 0.406). Multivariate analysis revealed higher HGS (odds ratio, OR = 1.142, 95% CI = 1.094-1.193, P < 0.001) and low-grade foraminal stenosis (OR = 0.403, 95% CI = 0.199-0.814, P = 0.011) were significantly associated with good analgesia after injection. The AUC values with 95% CI for HGS were 0.819 (0.718-0.920) in men and 0.800 (0.732-0.869) in women. In addition, HGS cutoff values for predicting good analgesic outcomes were 26.5 kg in men and 16.5 kg in women. Limitations: This study was conducted in a single center, and sample size was relatively small. The lack of physical performance evaluation did not fully meet the current criteria for sarcopenia. In addition, post-procedural clinical data associated with disability or quality of life could not be collected. Conclusion: In the present study, pre-procedural HGS was an independent predictor of analgesic efficacy after ESI in elderly patients with degenerative lumbar spinal disease. However, the PMI was not associated with pain relief after injection. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | American Society of Interventional Pain Physicians | - |
dc.relation.isPartOf | PAIN PHYSICIAN | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Analgesics / therapeutic use | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hand Strength | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Injections, Epidural / methods | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Pain / drug therapy | - |
dc.subject.MESH | Psoas Muscles | - |
dc.subject.MESH | Sarcopenia* / complications | - |
dc.subject.MESH | Sarcopenia* / drug therapy | - |
dc.subject.MESH | Spinal Diseases* / drug therapy | - |
dc.subject.MESH | Spinal Stenosis* / diagnosis | - |
dc.subject.MESH | Steroids | - |
dc.title | Influence of Handgrip Strength and Psoas Muscle Index on Analgesic Efficacy of Epidural Steroid Injection in Patients With Degenerative Lumbar Spinal Disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Shin Hyung Kim | - |
dc.contributor.googleauthor | Sang Jun Park | - |
dc.contributor.googleauthor | Kyung Bong Yoon | - |
dc.contributor.googleauthor | Eun-Kyung Jun | - |
dc.contributor.googleauthor | Jaehee Cho | - |
dc.contributor.googleauthor | Hee Jung Kim | - |
dc.contributor.localId | A06251 | - |
dc.contributor.localId | A04933 | - |
dc.contributor.localId | A02539 | - |
dc.contributor.localId | A00676 | - |
dc.relation.journalcode | J02460 | - |
dc.identifier.eissn | 2150-1149 | - |
dc.identifier.pmid | 36288597 | - |
dc.subject.keyword | handgrip strength | - |
dc.subject.keyword | pain management | - |
dc.subject.keyword | psoas muscle index | - |
dc.subject.keyword | sarcopenia | - |
dc.subject.keyword | spinal stenosis | - |
dc.subject.keyword | Epidural steroid injection | - |
dc.contributor.alternativeName | Kim, Heejung | - |
dc.contributor.affiliatedAuthor | 김희정 | - |
dc.contributor.affiliatedAuthor | 박상준 | - |
dc.contributor.affiliatedAuthor | 윤경봉 | - |
dc.contributor.affiliatedAuthor | 김신형 | - |
dc.citation.volume | 25 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | E1105 | - |
dc.citation.endPage | E1113 | - |
dc.identifier.bibliographicCitation | PAIN PHYSICIAN, Vol.25(7) : E1105-E1113, 2022-10 | - |
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