Cited 12 times in
Tumor size as a prognostic factor in limited-stage thymic epithelial tumors: A multicenter analysis
DC Field | Value | Language |
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dc.contributor.author | 정경영 | - |
dc.date.accessioned | 2022-11-24T00:39:17Z | - |
dc.date.available | 2022-11-24T00:39:17Z | - |
dc.date.issued | 2021-07 | - |
dc.identifier.issn | 0022-5223 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/190863 | - |
dc.description.abstract | Objective: The prognostic significance of tumor size in thymic epithelial tumors (TETs) has not been fully evaluated. We aimed to clarify the prognostic value of tumor size in limited-stage and advanced-stage TETs. Methods: Clinical records of patients with completely resected TETs were retrospectively collected from 4 tertiary centers between January 2000 and February 2013. Information on the Masaoka-Koga stage was available for 1215 patients (M-K group), and 433 patients were classified according to the eighth edition of the Tumor-Node-Metastasis staging system (TNM group). Limited-stage and advanced-stage TETs were defined according to whether they were confined within the surrounding fatty tissues without invasion. The optimal cutoff value was selected using a maximally selected log-rank statistic. Results: The median tumor size was 6.0 ± 2.8 cm in the M-K group and 6.5 ± 3.0 cm in the TNM group. In the multivariable analysis, tumor size had a significant effect on both overall survival (P = .003) and recurrence-free survival (P < .001) for limited-stage tumors (M-K stage I or II or TNM stage I), but not for advanced-stage tumors (M-K stage III or IV or TNM stage II-IV; P = .349 for overall survival and P = .439 for recurrence-free survival). The optimal cutoff value for tumor size was >5.5 cm for both overall survival and recurrence-free survival in limited-stage TETs. Conclusions: Tumor size is an independent prognostic factor in patients with completely resected limited-stage TETs and a cutoff value >5.5 cm might help clinicians enact proper treatment strategies and surveillance. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Mosby | - |
dc.relation.isPartOf | JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Neoplasms, Glandular and Epithelial* / diagnosis | - |
dc.subject.MESH | Neoplasms, Glandular and Epithelial* / mortality | - |
dc.subject.MESH | Neoplasms, Glandular and Epithelial* / pathology | - |
dc.subject.MESH | Neoplasms, Glandular and Epithelial* / surgery | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Thymus Neoplasms* / diagnosis | - |
dc.subject.MESH | Thymus Neoplasms* / mortality | - |
dc.subject.MESH | Thymus Neoplasms* / pathology | - |
dc.subject.MESH | Thymus Neoplasms* / surgery | - |
dc.title | Tumor size as a prognostic factor in limited-stage thymic epithelial tumors: A multicenter analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) | - |
dc.contributor.googleauthor | Jae Kwang Yun | - |
dc.contributor.googleauthor | Hyeong Ryul Kim | - |
dc.contributor.googleauthor | Dong Kwan Kim | - |
dc.contributor.googleauthor | Young Mog Shim | - |
dc.contributor.googleauthor | Young Tae Kim | - |
dc.contributor.googleauthor | Kyung Young Chung | - |
dc.identifier.doi | 10.1016/j.jtcvs.2020.05.048 | - |
dc.contributor.localId | A03571 | - |
dc.relation.journalcode | J01906 | - |
dc.identifier.eissn | 1097-685X | - |
dc.identifier.pmid | 32736865 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S002252232031271X | - |
dc.subject.keyword | recurrence | - |
dc.subject.keyword | risk factors | - |
dc.subject.keyword | survival | - |
dc.subject.keyword | thymic malignancy | - |
dc.subject.keyword | tumor size | - |
dc.contributor.alternativeName | Chung, Kyung Young | - |
dc.contributor.affiliatedAuthor | 정경영 | - |
dc.citation.volume | 162 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 309 | - |
dc.citation.endPage | 317 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, Vol.162(1) : 309-317, 2021-07 | - |
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