Cited 3 times in
A Cumulative Muscle Index and Its Parameters for Predicting Future Cognitive Decline: Longitudinal Outcomes of the ASPRA Cohort
DC Field | Value | Language |
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dc.contributor.author | 김우정 | - |
dc.date.accessioned | 2022-11-24T00:38:40Z | - |
dc.date.available | 2022-11-24T00:38:40Z | - |
dc.date.issued | 2021-07 | - |
dc.identifier.issn | 1661-7827 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/190852 | - |
dc.description.abstract | Sarcopenia and cognitive decline share the major risk factors of physical inactivity; previous studies have shown inconsistent associations. We aimed to identify the association of sarcopenia and its parameters with cognitive decline. The 3-year longitudinal outcomes of 1327 participants from the Aging Study of the Pyeongchang Rural Area (ASPRA) cohort were analyzed. Cognitive performance was evaluated using the Mini-Mental State Examination (MMSE), and sarcopenia was defined by the following: the original and revised Asian Working Group for Sarcopenia (AWGS), the original and revised European Working Group on Sarcopenia in Older People (EWGSOP), and the Cumulative Muscle Index (CMI), a novel index based on the number of impaired domains of sarcopenia. Approximately half of the participants showed meaningful cognitive decline. Sarcopenia by the original EWGSOP and the CMI were associated with cognitive decline. Only the CMI showed consistent predictability for cognitive impairment even with different criteria of the MMSE score (OR 1.23 [1.04-1.46]; OR 1.34 [1.12-1.59]; OR 1.22 [1.01-1.49], using the 1, 2, and 3 cut-off value, respectively). Of the CMI parameters, gait speed was satisfactorily predictive of 3-year cognitive impairment (OR 0.54 [0.30-0.97]). In conclusion, sarcopenia based on the CMI may be predictive of future cognitive impairment. Gait speed was the single most important indicator of cognitive decline. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aging | - |
dc.subject.MESH | Cognitive Dysfunction* / diagnosis | - |
dc.subject.MESH | Cognitive Dysfunction* / epidemiology | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Geriatric Assessment | - |
dc.subject.MESH | Hand Strength | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Muscles | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Sarcopenia* / diagnosis | - |
dc.subject.MESH | Sarcopenia* / epidemiology | - |
dc.title | A Cumulative Muscle Index and Its Parameters for Predicting Future Cognitive Decline: Longitudinal Outcomes of the ASPRA Cohort | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Psychiatry (정신과학교실) | - |
dc.contributor.googleauthor | Ji-Yeon Baek | - |
dc.contributor.googleauthor | Eunju Lee | - |
dc.contributor.googleauthor | Woo Jung Kim | - |
dc.contributor.googleauthor | Il-Young Jang | - |
dc.contributor.googleauthor | Hee-Won Jung | - |
dc.identifier.doi | 10.3390/ijerph18147350 | - |
dc.contributor.localId | A04906 | - |
dc.relation.journalcode | J01111 | - |
dc.identifier.eissn | 1660-4601 | - |
dc.identifier.pmid | 34299801 | - |
dc.subject.keyword | cognitive impairment | - |
dc.subject.keyword | gait speed | - |
dc.subject.keyword | sarcopenia | - |
dc.subject.keyword | sarcopenic parameters | - |
dc.contributor.alternativeName | Kim, Woo Jung | - |
dc.contributor.affiliatedAuthor | 김우정 | - |
dc.citation.volume | 18 | - |
dc.citation.number | 14 | - |
dc.citation.startPage | 7350 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, Vol.18(14) : 7350, 2021-07 | - |
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