Cited 2 times in
Clinical implication of neointimal burden in in-stent restenosis treated with drug-coated balloon
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김병극 | - |
dc.contributor.author | 김중선 | - |
dc.contributor.author | 안철민 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 최동훈 | - |
dc.contributor.author | 홍명기 | - |
dc.contributor.author | 홍성진 | - |
dc.contributor.author | 고영국 | - |
dc.date.accessioned | 2022-11-24T00:34:21Z | - |
dc.date.available | 2022-11-24T00:34:21Z | - |
dc.date.issued | 2021-09 | - |
dc.identifier.issn | 1522-1946 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/190784 | - |
dc.description.abstract | Background: Although drug-coated balloon (DCB) angioplasty is a well-established drug-eluting stent (DES) in-stent restenosis (ISR) strategy, there are minimal data regarding the association of neointimal burden on optical coherence tomography (OCT) before and after DCB and adverse clinical events. This study aimed to investigate the clinical impact of neointimal burden measured with OCT in patients with DES ISR after DCB angioplasty. Methods: From 2010 through 2013, a total of 122 patients with 122 ISR lesions were treated with DCB, which was preceded and followed by OCT examination. Major adverse cardiac events (MACE, a composite occurrence of cardiovascular cardiac death, nonfatal myocardial infarction [MI], or target lesion revascularization [TLR]) were evaluated. Results: MACE occurred in 27 patients (4 nonfatal MIs and 23 TLRs) during the follow-up (median: 55.3 months, interquartile range 43.1-66.0). The mean lumen area was significantly smaller (3.21 ± 2.42 mm2 vs. 4.80 ± 2.53 mm2 , p = .005) and the mean percentage of neointimal volume derived by OCT was greater (49.3 ± 9.2% vs. 38.3 ± 17.5%, p = .006) in patients with MACE before DCB angioplasty. The pre-procedural mean percentage of neointimal volume (cut-off 50%, area under the receiver operating characteristic [ROC] curve = 0.644, 95% confidence interval [CI] = 0.531-0.758, p = .022) and post-procedural mean percentage of neointimal volume (cut-off 25%, area under ROC curve = 0.659, 95% CI = 0.546-0.773, p = .012) were identified as significant parameters to predict MACE. Conclusion: The OCT-derived mean percentages of neointimal volume before and after DCB angioplasty can be important parameters for predicting future MACE in patients with DES ISR. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley-Liss | - |
dc.relation.isPartOf | CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Coronary Angiography | - |
dc.subject.MESH | Coronary Restenosis* / diagnostic imaging | - |
dc.subject.MESH | Coronary Restenosis* / etiology | - |
dc.subject.MESH | Drug-Eluting Stents* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Percutaneous Coronary Intervention* | - |
dc.subject.MESH | Pharmaceutical Preparations* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Substances | - |
dc.title | Clinical implication of neointimal burden in in-stent restenosis treated with drug-coated balloon | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jung-Hee Lee | - |
dc.contributor.googleauthor | Ung Kim | - |
dc.contributor.googleauthor | Jung-Sun Kim | - |
dc.contributor.googleauthor | Sung-Jin Hong | - |
dc.contributor.googleauthor | Chul-Min Ahn | - |
dc.contributor.googleauthor | Byeong-Keuk Kim | - |
dc.contributor.googleauthor | Young-Guk Ko | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Myeong-Ki Hong | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.identifier.doi | 10.1002/ccd.29211 | - |
dc.contributor.localId | A00493 | - |
dc.contributor.localId | A00961 | - |
dc.contributor.localId | A02269 | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A04053 | - |
dc.contributor.localId | A04391 | - |
dc.contributor.localId | A04403 | - |
dc.contributor.localId | A00127 | - |
dc.relation.journalcode | J00471 | - |
dc.identifier.eissn | 2451-9456 | - |
dc.identifier.pmid | 32852874 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/ccd.29211 | - |
dc.subject.keyword | drug-eluting balloon | - |
dc.subject.keyword | in-stent restenosis | - |
dc.subject.keyword | neointima | - |
dc.subject.keyword | optical coherence tomography | - |
dc.subject.keyword | treatment outcome | - |
dc.contributor.alternativeName | Kim, Byeong Keuk | - |
dc.contributor.affiliatedAuthor | 김병극 | - |
dc.contributor.affiliatedAuthor | 김중선 | - |
dc.contributor.affiliatedAuthor | 안철민 | - |
dc.contributor.affiliatedAuthor | 장양수 | - |
dc.contributor.affiliatedAuthor | 최동훈 | - |
dc.contributor.affiliatedAuthor | 홍명기 | - |
dc.contributor.affiliatedAuthor | 홍성진 | - |
dc.contributor.affiliatedAuthor | 고영국 | - |
dc.citation.volume | 98 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 493 | - |
dc.citation.endPage | 502 | - |
dc.identifier.bibliographicCitation | CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Vol.98(3) : 493-502, 2021-09 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.