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Age-adjusted quick Sequential Organ Failure Assessment score for predicting mortality and disease severity in children with infection: a systematic review and meta-analysis
DC Field | Value | Language |
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dc.contributor.author | 구청모 | - |
dc.contributor.author | 김문규 | - |
dc.contributor.author | 김하얀 | - |
dc.contributor.author | 배고은 | - |
dc.contributor.author | 윤서희 | - |
dc.contributor.author | 은소현 | - |
dc.contributor.author | 이명지 | - |
dc.contributor.author | 배고은 | - |
dc.date.accessioned | 2021-12-28T17:41:20Z | - |
dc.date.available | 2021-12-28T17:41:20Z | - |
dc.date.issued | 2021-11 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/187224 | - |
dc.description.abstract | We assessed the diagnostic accuracy of the age-adjusted quick Sequential Organ Failure Assessment score (qSOFA) for predicting mortality and disease severity in pediatric patients with suspected or confirmed infection. We conducted a systematic search of PubMed, EMBASE, the Cochrane Library, and Web of Science. Eleven studies with a total of 172,569 patients were included in the meta-analysis. The pooled sensitivity, specificity, and diagnostic odds ratio of the age-adjusted qSOFA for predicting mortality and disease severity were 0.69 (95% confidence interval [CI] 0.53-0.81), 0.71 (95% CI 0.36-0.91), and 6.57 (95% CI 4.46-9.67), respectively. The area under the summary receiver-operating characteristic curve was 0.733. The pooled sensitivity and specificity for predicting mortality were 0.73 (95% CI 0.66-0.79) and 0.63 (95% CI 0.21-0.92), respectively. The pooled sensitivity and specificity for predicting disease severity were 0.73 (95% CI 0.21-0.97) and 0.72 (95% CI 0.11-0.98), respectively. The performance of the age-adjusted qSOFA for predicting mortality and disease severity was better in emergency department patients than in intensive care unit patients. The age-adjusted qSOFA has moderate predictive power and can help in rapidly identifying at-risk children, but its utility may be limited by its insufficient sensitivity. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Age-adjusted quick Sequential Organ Failure Assessment score for predicting mortality and disease severity in children with infection: a systematic review and meta-analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | Sohyun Eun | - |
dc.contributor.googleauthor | Haemin Kim | - |
dc.contributor.googleauthor | Ha Yan Kim | - |
dc.contributor.googleauthor | Myeongjee Lee | - |
dc.contributor.googleauthor | Go Eun Bae | - |
dc.contributor.googleauthor | Heoungjin Kim | - |
dc.contributor.googleauthor | Chung Mo Koo | - |
dc.contributor.googleauthor | Moon Kyu Kim | - |
dc.contributor.googleauthor | Seo Hee Yoon | - |
dc.identifier.doi | 10.1038/s41598-021-01271-w | - |
dc.contributor.localId | A06014 | - |
dc.contributor.localId | A05689 | - |
dc.contributor.localId | A01091 | - |
dc.contributor.localId | A06076 | - |
dc.contributor.localId | A02563 | - |
dc.contributor.localId | A06053 | - |
dc.contributor.localId | A05996 | - |
dc.relation.journalcode | J02646 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.pmid | 34737369 | - |
dc.contributor.alternativeName | Koo, Chung Mo | - |
dc.contributor.affiliatedAuthor | 구청모 | - |
dc.contributor.affiliatedAuthor | 김문규 | - |
dc.contributor.affiliatedAuthor | 김하얀 | - |
dc.contributor.affiliatedAuthor | 배고은 | - |
dc.contributor.affiliatedAuthor | 윤서희 | - |
dc.contributor.affiliatedAuthor | 은소현 | - |
dc.contributor.affiliatedAuthor | 이명지 | - |
dc.citation.volume | 11 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 21699 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, Vol.11(1) : 21699, 2021-11 | - |
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