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Understanding the genetics of systemic lupus erythematosus using Bayesian statistics and gene network analysis
DC Field | Value | Language |
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dc.contributor.author | 신재일 | - |
dc.contributor.author | 이금화 | - |
dc.contributor.author | 이광섭 | - |
dc.date.accessioned | 2021-12-28T17:36:25Z | - |
dc.date.available | 2021-12-28T17:36:25Z | - |
dc.date.issued | 2021-05 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/187179 | - |
dc.description.abstract | The publication of genetic epidemiology meta-analyses has increased rapidly, but it has been suggested that many of the statistically significant results are false positive. In addition, most such meta-analyses have been redundant, duplicate, and erroneous, leading to research waste. In addition, since most claimed candidate gene associations were false-positives, correctly interpreting the published results is important. In this review, we emphasize the importance of interpreting the results of genetic epidemiology meta-analyses using Bayesian statistics and gene network analysis, which could be applied in other diseases. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Korean Pediatric Society | - |
dc.relation.isPartOf | Clinical and Experimental Pediatrics | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Understanding the genetics of systemic lupus erythematosus using Bayesian statistics and gene network analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | Seoung Wan Nam | - |
dc.contributor.googleauthor | Kwang Seob Lee | - |
dc.contributor.googleauthor | Jae Won Yang | - |
dc.contributor.googleauthor | Younhee Ko | - |
dc.contributor.googleauthor | Michael Eisenhut | - |
dc.contributor.googleauthor | Keum Hwa Lee | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.contributor.googleauthor | Andreas Kronbichler | - |
dc.identifier.doi | 10.3345/cep.2020.00633 | - |
dc.contributor.localId | A02142 | - |
dc.relation.journalcode | J03867 | - |
dc.identifier.eissn | 2713-4148 | - |
dc.identifier.pmid | 32683804 | - |
dc.subject.keyword | Bayesian false-discovery probability | - |
dc.subject.keyword | False-positive report probability | - |
dc.subject.keyword | Protein-protein interaction | - |
dc.subject.keyword | STRING database | - |
dc.subject.keyword | Systemic lupus erythematosus | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | 신재일 | - |
dc.citation.volume | 64 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 208 | - |
dc.citation.endPage | 222 | - |
dc.identifier.bibliographicCitation | Clinical and Experimental Pediatrics, Vol.64(5) : 208-222, 2021-05 | - |
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