Clozapine 치료에 따른 일과성 야뇨증

Abstract

We experienced four cases of transient enuresis in chronic schizophrenic patients following clozapine treatment. One case developed nocturnal enuresis only and the other three cases developed nocturnal enuresis combined with a dose of more than 300㎎/day. Nocturnal enuresis was managed by behavioral education, but for one case nocturnal enuresis was managed by reducing clozapine dosage. It is suggested that clozapine-related nocturnal enuresis is doserelated and tansient. Since Nocturnal enuresis may be embarassing for patients and not readily volunteered, it is helpful for the physician to inquire carefully about them