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기관지 천식에서 급성 발작기와 호전기의 Interleukin - 6 치의 변동에 관한 연구
DC Field | Value | Language |
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dc.contributor.author | 김동수 | - |
dc.date.accessioned | 2021-12-27T16:55:07Z | - |
dc.date.available | 2021-12-27T16:55:07Z | - |
dc.date.issued | 1995-06 | - |
dc.identifier.issn | 1225-679X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/186247 | - |
dc.description.abstract | Asthma is a chronic obstructive airway disease. It is characterized by episodic exacerbations of reversible airflow obstruction along with bronchial hyperreactivity and airway inflammation. The airway inflammation is now a major focus of investigation because of its critical role in pathogenesis of asthma. Interleukin-6(IL-6) is a multifunctional cytokine, which has a major role in induction of inflammatory and immune reaction. Althouth the exact functions of IL-6 in asthma pathogenesis are unknown, we studied serun IL-6 level in acute asthma attack and exercise-induced asthma during acute and convalescent phase and tried to investigate their relationship with the clinical menifestation of in asthma. The results were as follows ' 1) In acute asthma attack, the mean serum IL-6 level markedly increased to 31.6 pg/ml at acute stage and decreased to 16.0 pg/ml at convalescent stage(P<0.01). 2) In exercise-induced asthma, the mean serum IL-6 level before exercise was 7.9 pg/ml and after-exercise level was 7.7 pg/ml. There was no significant difference. 3) In pneumonia, serum IL-6 level increased to 25.7 pg/ml at acute stage and decreased to 13.3 pg/ml at convalescent stage(P<0.05). 4) There was no significant correlation between serum IL-6 level at acute stage and the severity of clinical manifestation. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한 소아알레르기 호흡기학회 | - |
dc.relation.isPartOf | Pediatric Allergy and Respiratory Disease(소아알레르기 호흡기학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 기관지 천식에서 급성 발작기와 호전기의 Interleukin - 6 치의 변동에 관한 연구 | - |
dc.title.alternative | The Interleukin - 6 Level in Acute Athma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | ;Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | 강혜영 | - |
dc.contributor.googleauthor | 김동수 | - |
dc.contributor.googleauthor | 김규언 | - |
dc.contributor.googleauthor | 정병주 | - |
dc.contributor.googleauthor | 이기영 | - |
dc.contributor.localId | A00405 | - |
dc.relation.journalcode | J02476 | - |
dc.contributor.alternativeName | Kim, Dong Soo | - |
dc.contributor.affiliatedAuthor | 김동수 | - |
dc.citation.volume | 5 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 104 | - |
dc.citation.endPage | 111 | - |
dc.identifier.bibliographicCitation | Pediatric Allergy and Respiratory Disease (소아알레르기 호흡기학회지), Vol.5(1) : 104-111, 1995-06 | - |
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