Cited 8 times in
Polymorphisms in the interleukin genes and chronic periodontitis: A field synopsis and revaluation by Bayesian approaches
DC Field | Value | Language |
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dc.contributor.author | 신재일 | - |
dc.date.accessioned | 2021-09-29T01:03:16Z | - |
dc.date.available | 2021-09-29T01:03:16Z | - |
dc.date.issued | 2021-02 | - |
dc.identifier.issn | 1043-4666 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/184165 | - |
dc.description.abstract | Periodontitis is a high prevalent disease into the clinical dentistry. Genetic variations in interleukins (IL) genes were associated with chronic periodontitis (CP) and were focus of several meta-analyses. This study aimed to assess the noteworthiness in the meta-analyses by means of a Bayesian approach to determinate possible false report associations. A systematic search was performed for meta-analyses with associations between gene polymorphisms in interleukins and CP. The calculations for the False-Positive Rate Probability (FPRP) and the Bayesian False Discovery Probability (BFDP) were performed to assess the noteworthiness with a statistical power of 1.2 and 1.5 of Odds Ratio at a prior probability of 10-3 and 10-6. As results, eight meta-analyses approaching the IL1A/rs1800587, IL1B/rs1143634, IL1RN/rs2234663, IL4/rs2243250, IL6/rs1800795/rs1800796, IL17A/rs2275913 and IL18/rs1946518/rs187238 polymorphisms have been identified. Twenty-two from 270 calculations (8.15%) were noteworthy. Herein, we have identified the IL1A and IL1B polymorphisms as noteworthy biomarkers for CP susceptibility. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | CYTOKINE | - |
dc.publisher | CYTOKINE | - |
dc.relation.isPartOf | CYTOKINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Polymorphisms in the interleukin genes and chronic periodontitis: A field synopsis and revaluation by Bayesian approaches | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | Felipe Rodolfo Pereira da Silva | - |
dc.contributor.googleauthor | Larissa Dos Santos Pessoa | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.contributor.googleauthor | Even Herlany Pereira Alves | - |
dc.contributor.googleauthor | Reyce Santos Koga | - |
dc.contributor.googleauthor | Camila Valente Smith | - |
dc.contributor.googleauthor | Daniel Fernando Pereira Vasconcelos | - |
dc.contributor.googleauthor | Anna Carolina Toledo da Cunha Pereira | - |
dc.identifier.doi | 10.1016/j.cyto.2020.155361 | - |
dc.contributor.localId | A02142 | - |
dc.relation.journalcode | J00691 | - |
dc.identifier.eissn | 1096-0023 | - |
dc.identifier.pmid | 33223448 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S104346662030377 | - |
dc.subject.keyword | Alleles | - |
dc.subject.keyword | Genetic variations | - |
dc.subject.keyword | Odds ratio | - |
dc.subject.keyword | Periodontal diseases | - |
dc.subject.keyword | Risk factors | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | 신재일 | - |
dc.citation.volume | 138 | - |
dc.citation.startPage | 155361 | - |
dc.identifier.bibliographicCitation | CYTOKINE, Vol.138 : 155361, 2021-02 | - |
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