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Unmet Psychosocial Needs of Patients with Newly Diagnosed Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea
DC Field | Value | Language |
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dc.contributor.author | 천재희 | - |
dc.date.accessioned | 2021-09-29T00:30:59Z | - |
dc.date.available | 2021-09-29T00:30:59Z | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/183885 | - |
dc.description.abstract | Background/aims: Limited data are available regarding psychosocial distress at the time of diagnosis of ulcerative colitis (UC). We investigated the psychosocial burden and factors related to poor health-related quality of life (HRQL) among patients newly diagnosed with moderate-to-severe UC who were affiliated with the nationwide prospective cohort study. Methods: Within the first 4 weeks of UC diagnosis, all patients were assessed using the Hospital Anxiety and Depression Scale (HADS), Work Productivity and Activity Impairment questionnaire, Inflammatory Bowel Disease Questionnaire (IBDQ), and 12-Item Short Form (SF-12) health survey. A multiple linear regression model was used to identify factors associated with HRQL. Results: Between August 2014 and February 2017, 355 patients completed questionnaires. Significant mood disorders requiring psychological interventions, defined by a HADS score ≥11, were identified in 16.7% (anxiety) and 20.6% (depression) of patients. Patients with severe disease were more likely to have presenteeism, loss of work productivity, and activity loss than those with moderate disease (all p<0.05). Significant mood disorders had the strongest negative relationship with total IBDQ score, which indicates disease-specific HRQL (β coefficient: -22.1 for depression and -40.0 for anxiety, p<0.001). The scores of all SF-12 dimensions, which indicate general HRQL, were remarkably decreased in the study population compared indirectly with previously reported scores in the general population. The Mayo score, C-reactive protein level, and white blood cell count showed significant negative associations with the IBDQ score (p<0.05). Conclusions: Psychosocial screening and timely interventions should be incorporated into the initial care of patients newly diagnosed with UC. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Editorial Office of Gut and Liver | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Unmet Psychosocial Needs of Patients with Newly Diagnosed Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jung Rock Moon | - |
dc.contributor.googleauthor | Chang Kyun Lee | - |
dc.contributor.googleauthor | Sung Noh Hong | - |
dc.contributor.googleauthor | Jong Pil Im | - |
dc.contributor.googleauthor | Byong Duk Ye | - |
dc.contributor.googleauthor | Jae Myung Cha | - |
dc.contributor.googleauthor | Sung-Ae Jung | - |
dc.contributor.googleauthor | Kang-Moon Lee | - |
dc.contributor.googleauthor | Dong Il Park | - |
dc.contributor.googleauthor | Yoon Tae Jeen | - |
dc.contributor.googleauthor | Young Sook Park | - |
dc.contributor.googleauthor | Jae Hee Cheon | - |
dc.contributor.googleauthor | Hyesung Kim | - |
dc.contributor.googleauthor | BoJeong Seo | - |
dc.contributor.googleauthor | Youngdoe Kim | - |
dc.contributor.googleauthor | Hyo Jong Kim | - |
dc.identifier.doi | 10.5009/gnl19107 | - |
dc.contributor.localId | A04030 | - |
dc.relation.journalcode | J00954 | - |
dc.identifier.eissn | 2005-1212 | - |
dc.identifier.pmid | 31533398 | - |
dc.subject.keyword | Anxiety | - |
dc.subject.keyword | Colitis | - |
dc.subject.keyword | Depression | - |
dc.subject.keyword | Patient reported outcome measures | - |
dc.subject.keyword | Quality of life | - |
dc.subject.keyword | ulcerative | - |
dc.contributor.alternativeName | Cheon, Jae Hee | - |
dc.contributor.affiliatedAuthor | 천재희 | - |
dc.citation.volume | 14 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 459 | - |
dc.citation.endPage | 467 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, Vol.14(4) : 459-467, 2020-07 | - |
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