Cited 56 times in
Ten-Year Oncologic Outcomes Following Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium
DC Field | Value | Language |
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dc.contributor.author | 나군호 | - |
dc.date.accessioned | 2020-02-11T06:18:56Z | - |
dc.date.available | 2020-02-11T06:18:56Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 0022-5347 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/174631 | - |
dc.description.abstract | PURPOSE: Radical cystectomy is the gold standard for nonmetastatic muscle invasive bladder cancer and for refractory nonmuscle invasive disease. Compared to open radical cystectomy, robot-assisted radical cystectomy has been shown to provide comparable early oncologic outcomes and improved perioperative outcomes. However, there is a paucity of data on long-term oncologic outcomes and concerns about a higher incidence of local recurrence after robot-assisted radical cystectomy. We report 10-year oncologic outcomes following robot-assisted radical cystectomy using a multinational database. MATERIALS AND METHODS: We retrospectively reviewed the prospective International Robotic Cystectomy Consortium database. Consecutive patients who underwent robot-assisted radical cystectomy 10 years ago or earlier were included in analysis. Data were reviewed for demographics, and perioperative, pathological and oncologic outcomes. Kaplan-Meier curves were used to depict recurrence-free, disease specific and overall survival. Multivariate stepwise Cox regression models were applied to identify variables associated with recurrence-free, disease specific and overall survival. RESULTS: We identified 446 patients with a median age of 67 years (IQR 59-76). Of the patients 10% received neoadjuvant chemotherapy, 51% experienced any complication, 23% had high grade complications and 4% died within 3 months of robot-assisted radical cystectomy. Disease was pT3 or greater in 43% of patients and pN+ in 24% while a positive soft tissue surgical margin was observed in 7%. At a median followup of 5 years (IQR 2-10, maximum 14) local and distant recurrence had developed in 15% and 29% of patients, respectively. Ten-year recurrence-free, disease specific and overall survival rates were 59%, 65% and 35%, respectively. Patients with pT3 or greater and pN+ disease showed worse recurrence-free, disease specific and overall survival. CONCLUSIONS: Long-term oncologic outcomes, and recurrence rates and patterns after robot-assisted radical cystectomy seem comparable to those in open series. Advanced disease stage and positive surgical margins remain the main determinants of survival after radical cystectomy. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | JOURNAL OF UROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Cystectomy/methods* | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Europe/epidemiology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Forecasting* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Invasiveness | - |
dc.subject.MESH | Neoplasm Recurrence, Local/epidemiology* | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Robotic Surgical Procedures/methods* | - |
dc.subject.MESH | Survival Rate/trends | - |
dc.subject.MESH | United States/epidemiology | - |
dc.subject.MESH | Urinary Bladder Neoplasms/mortality | - |
dc.subject.MESH | Urinary Bladder Neoplasms/pathology | - |
dc.subject.MESH | Urinary Bladder Neoplasms/surgery* | - |
dc.title | Ten-Year Oncologic Outcomes Following Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨의학교실) | - |
dc.contributor.googleauthor | Hussein, Ahmed A. | - |
dc.contributor.googleauthor | Elsayed, Ahmed S. | - |
dc.contributor.googleauthor | Aldhaam, Naif A. | - |
dc.contributor.googleauthor | Jing, Zhe | - |
dc.contributor.googleauthor | Osei, Jennifer | - |
dc.contributor.googleauthor | Kaouk, Jihad | - |
dc.contributor.googleauthor | Redorta, Juan Palou | - |
dc.contributor.googleauthor | Menon, Mani | - |
dc.contributor.googleauthor | Peabody, James | - |
dc.contributor.googleauthor | Dasgupta, Prokar | - |
dc.contributor.googleauthor | Khan, Mohammed Shamim | - |
dc.contributor.googleauthor | Mottrie, Alexandre | - |
dc.contributor.googleauthor | Stockle, Michael | - |
dc.contributor.googleauthor | Hemal, Ashok | - |
dc.contributor.googleauthor | Richstone, Lee | - |
dc.contributor.googleauthor | Hosseini, Abolfazl | - |
dc.contributor.googleauthor | Wiklund, Peter | - |
dc.contributor.googleauthor | Schanne, Francis | - |
dc.contributor.googleauthor | Kim, Eric | - |
dc.contributor.googleauthor | Ho Rha, Koon | - |
dc.contributor.googleauthor | Guru, Khurshid A. | - |
dc.identifier.doi | 10.1097/JU.0000000000000386 | - |
dc.contributor.localId | A01227 | - |
dc.relation.journalcode | J01921 | - |
dc.identifier.eissn | 1527-3792 | - |
dc.identifier.pmid | 31188729 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00076734-201911000-00071&LSLINK=80&D=ovft | - |
dc.subject.keyword | cystectomy | - |
dc.subject.keyword | mortality | - |
dc.subject.keyword | recurrence | - |
dc.subject.keyword | robotic surgical procedures | - |
dc.subject.keyword | urinary bladder neoplasms | - |
dc.contributor.alternativeName | Rha, Koon Ho | - |
dc.contributor.affiliatedAuthor | 나군호 | - |
dc.citation.volume | 202 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 927 | - |
dc.citation.endPage | 935 | - |
dc.identifier.bibliographicCitation | JOURNAL OF UROLOGY, Vol.202(5) : 927-935, 2019 | - |
dc.identifier.rimsid | 63608 | - |
dc.type.rims | ART | - |
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