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Clusterin is highly expressed in tubular complexes during spontaneous pancreatitis of spontaneous hypertensive rats
DC Field | Value | Language |
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dc.contributor.author | 남기택 | - |
dc.date.accessioned | 2019-01-15T16:55:54Z | - |
dc.date.available | 2019-01-15T16:55:54Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0916-7250 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/166725 | - |
dc.description.abstract | Pancreatitis is an inflammatory disorder of pancreas which leads to varying degrees of pancreatic endocrine and exocrine dysfunction and manifests in either acute or chronic forms. Spontaneous pancreatitis in experimental animals has rarely been reported. Here, we found acute to chronic courses of spontaneous pancreatitis in spontaneously hypertensive rats (SHRs), showing the formation of tubular complexes (TCs) and enhanced islet regeneration. We investigated the expression pattern of clusterin in the pancreas of SHRs based on immunohistochemistry (IHC). IHC analysis revealed the strong expression of clusterin in dedifferentiated duct-like cells and regenerative islets of TCs. These results imply that clusterin might be involved in the formation of TCs and parenchymal regeneration during rat pancreatitis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Japanese Society of Veterinary Science | - |
dc.relation.isPartOf | JOURNAL OF VETERINARY MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Clusterin is highly expressed in tubular complexes during spontaneous pancreatitis of spontaneous hypertensive rats | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | BioMedical Science Institute (의생명과학부) | - |
dc.contributor.googleauthor | Jun Won PARK | - |
dc.contributor.googleauthor | Ki Taek NAM | - |
dc.contributor.googleauthor | Jae Hoon SHIN | - |
dc.contributor.googleauthor | Il Yong KIM | - |
dc.contributor.googleauthor | Kyung Mi CHOI | - |
dc.contributor.googleauthor | Kyung-Jin ROH | - |
dc.contributor.googleauthor | Seung Hyun OH | - |
dc.contributor.googleauthor | Young-Min YUN | - |
dc.contributor.googleauthor | Jun-Gyo SUH | - |
dc.contributor.googleauthor | Yang-Seok OH | - |
dc.contributor.googleauthor | Yeo Sung YOON | - |
dc.contributor.googleauthor | Je Kyung SEONG | - |
dc.identifier.doi | 10.1292/jvms.18-0205 | - |
dc.contributor.localId | A01243 | - |
dc.relation.journalcode | J01926 | - |
dc.identifier.eissn | 1347-7439 | - |
dc.identifier.pmid | 30111670 | - |
dc.subject.keyword | clusterin | - |
dc.subject.keyword | pancreatitis | - |
dc.subject.keyword | spontaneous hypertensive rat | - |
dc.subject.keyword | tubular complex | - |
dc.contributor.alternativeName | Nam, Ki Taek | - |
dc.contributor.affiliatedAuthor | 남기택 | - |
dc.citation.volume | 80 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1553 | - |
dc.citation.endPage | 1557 | - |
dc.identifier.bibliographicCitation | JOURNAL OF VETERINARY MEDICAL SCIENCE, Vol.80(10) : 1553-1557, 2018 | - |
dc.identifier.rimsid | 57994 | - |
dc.type.rims | ART | - |
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