Cited 3 times in
Early features of Kawasaki disease with pyuria in febrile infants younger than 6 months
DC Field | Value | Language |
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dc.contributor.author | 윤서희 | - |
dc.contributor.author | 안종균 | - |
dc.contributor.author | 김동수 | - |
dc.date.accessioned | 2018-12-28T02:05:45Z | - |
dc.date.available | 2018-12-28T02:05:45Z | - |
dc.date.issued | 2018 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/166249 | - |
dc.description.abstract | BACKGROUND: Children with Kawasaki disease (KD) and pyuria have been misdiagnosed with urinary tract infection (UTI). We compared clinical and laboratory features at admission between two groups of infants under 6 months of age who showed initial pyuria, to identify the initial clues suggestive of KD. METHODS: We retrospectively reviewed the medical records of children with fever who were under 6 months of age with pyuria, over a 10-year period (2007-2017). We included infants with sterile pyuria who were finally diagnosed with KD and those with UTI. RESULTS: During the period investigated, 12 (9.9%) KD patients with sterile pyuria and 378 infants with UTI were included in this study. Older age (P < 0.01), a longer duration of fever; total and before admission (P < 0.01), more negative nitrite test (P < 0.01), higher platelet count (P = 0.04), increased C-reactive protein (CRP) (P < 0.01) and erythrocyte sedimentation rate (ESR) (P < 0.01), were identified as initial features of infants finally diagnosed with KD. In the receiver operating characteristic analysis, optimal cut-off values of 509 k/μL for platelet count, 60 mg/L for CRP, and 68 mm/H for ESR were selected. Patients with ESR > 68 mm/hr had a ninefold higher odds of KD compared to those with lower ESR levels (odds ratio: 8.963, 95% confidence intervals: 1.936-41.493, P = 0.005), whereas CRP and platelet count could not significantly increase in the odds of KD at a cut-off point. CONCLUSION: Persistent fever, elevated ESR, and negative urine nitrite test can serve as early clues to suspect KD in febrile infants with pyuria. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | BioMed Central | - |
dc.relation.isPartOf | BMC PEDIATRICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Early features of Kawasaki disease with pyuria in febrile infants younger than 6 months | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아청소년과학교실) | - |
dc.contributor.googleauthor | Seo Hee Yoon | - |
dc.contributor.googleauthor | Dong Soo Kim | - |
dc.contributor.googleauthor | Jong Gyun Ahn | - |
dc.identifier.doi | 10.1186/s12887-018-1362-x | - |
dc.contributor.localId | A02563 | - |
dc.contributor.localId | A02261 | - |
dc.contributor.localId | A00405 | - |
dc.relation.journalcode | J03399 | - |
dc.identifier.eissn | 1471-2431 | - |
dc.identifier.pmid | 30572858 | - |
dc.identifier.url | https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-018-1362-x | - |
dc.subject.keyword | Differential diagnosis | - |
dc.subject.keyword | Fever | - |
dc.subject.keyword | Infant | - |
dc.subject.keyword | Kawasaki disease | - |
dc.subject.keyword | Urinary tract infection | - |
dc.contributor.alternativeName | Yoon, Seo Hee | - |
dc.contributor.affiliatedAuthor | 윤서희 | - |
dc.contributor.affiliatedAuthor | 안종균 | - |
dc.contributor.affiliatedAuthor | 김동수 | - |
dc.citation.volume | 18 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 389 | - |
dc.identifier.bibliographicCitation | BMC PEDIATRICS, Vol.18(1) : 389, 2018 | - |
dc.identifier.rimsid | 58248 | - |
dc.type.rims | ART | - |
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