Cited 8 times in
Serum high-density lipoprotein cholesterol concentration and functional state: The Korean Urban Rural Elderly (KURE) Study
DC Field | Value | Language |
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dc.contributor.author | 김창오 | - |
dc.contributor.author | 김현창 | - |
dc.contributor.author | 이유미 | - |
dc.contributor.author | 이은영 | - |
dc.contributor.author | 이주미 | - |
dc.contributor.author | 최한솔 | - |
dc.date.accessioned | 2018-07-20T07:29:23Z | - |
dc.date.available | 2018-07-20T07:29:23Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0167-4943 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/160213 | - |
dc.description.abstract | BACKGROUND: Functional state and cholesterol metabolism are important for older adults; however, this association has not been fully investigated among community-dwelling older adults. Thus, we investigated the association of HDL cholesterol with multiple functional state measures in an elderly Korean population. METHODS: This cross-sectional analysis included 3514 participants, aged 65 years or older, who participated in baseline health assessment for the Korean Urban Rural Elderly cohort study from 2012 to 2015. HDL cholesterol concentration was analyzed using both continuous and categorical variables. Functional state was assessed by the mini-mental state examination (MMSE), activities of daily living (ADL) scale, instrumental activities of daily living (IADL) scale, timed up-and go (TUG) test, and chair-rise test (CRT). Multiple logistic regression models were used to investigate independent association between HDL cholesterol and functional state, after adjusting for sex, age, body mass index, systolic blood pressure, fasting glucose, lipid-lowering drug, history of cancer and cardiovascular disease, and health behaviors. RESULTS: HDL cholesterol concentration was significantly associated with MMSE, ADL, IADL, TUG, and CRT in the unadjusted model. After adjustment for covariates, the association remained significant for MMSE (standardized β=0.059, p=0.001), ADL (standardized β=-0.053, p=0.004), and CRT (standardized β=-0.037, p=0.037). In fully-adjusted model, Participants who had a lower HDL concentration (<40mg/dL) showed significantly increased odds for having MMSE decline (OR 1.451, 95% CI 1.119-1.883) and ADL dependency (OR 2.251, 95% CI 1.119-4.526), compared reference group (≥60mg/dL). CONCLUSIONS: Higher HDL cholesterol concentration was associated with better functional state among Korean older adults. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier Biomedical Press | - |
dc.relation.isPartOf | ARCHIVES OF GERONTOLOGY AND GERIATRICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Activities of Daily Living* | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Cholesterol, HDL/blood* | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Geriatric Assessment* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Logistic Models | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Rural Population | - |
dc.title | Serum high-density lipoprotein cholesterol concentration and functional state: The Korean Urban Rural Elderly (KURE) Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Hansol Choi | - |
dc.contributor.googleauthor | Hyeon Chang Kim | - |
dc.contributor.googleauthor | Katherine M. Stefani | - |
dc.contributor.googleauthor | Ju-Mi Lee | - |
dc.contributor.googleauthor | Young Mi Yoon | - |
dc.contributor.googleauthor | Eun Young Lee | - |
dc.contributor.googleauthor | Kyoung Min Kim | - |
dc.contributor.googleauthor | Yumie Rhee | - |
dc.contributor.googleauthor | Yoosik Youm | - |
dc.contributor.googleauthor | Chang Oh Kim | - |
dc.identifier.doi | 10.1016/j.archger.2017.04.002 | - |
dc.contributor.localId | A01044 | - |
dc.contributor.localId | A01142 | - |
dc.contributor.localId | A03012 | - |
dc.contributor.localId | A03042 | - |
dc.contributor.localId | A03157 | - |
dc.contributor.localId | A05433 | - |
dc.relation.journalcode | J00219 | - |
dc.identifier.eissn | 1872-6976 | - |
dc.identifier.pmid | 28415035 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0167494317302091 | - |
dc.subject.keyword | Cognitive function | - |
dc.subject.keyword | Elderly | - |
dc.subject.keyword | Functional state | - |
dc.subject.keyword | HDL cholesterol | - |
dc.subject.keyword | Physical function | - |
dc.contributor.alternativeName | Kim, Chang Oh | - |
dc.contributor.alternativeName | Kim, Hyeon Chang | - |
dc.contributor.alternativeName | Rhee, Yumie | - |
dc.contributor.alternativeName | Lee, Eun Young | - |
dc.contributor.alternativeName | Lee, Ju Mi | - |
dc.contributor.alternativeName | Choi, Han Sol | - |
dc.contributor.affiliatedAuthor | Kim, Chang Oh | - |
dc.contributor.affiliatedAuthor | Kim, Hyeon Chang | - |
dc.contributor.affiliatedAuthor | Rhee, Yumie | - |
dc.contributor.affiliatedAuthor | Lee, Eun Young | - |
dc.contributor.affiliatedAuthor | Lee, Ju Mi | - |
dc.contributor.affiliatedAuthor | Choi, Han Sol | - |
dc.citation.volume | 71 | - |
dc.citation.startPage | 115 | - |
dc.citation.endPage | 121 | - |
dc.identifier.bibliographicCitation | ARCHIVES OF GERONTOLOGY AND GERIATRICS, Vol.71 : 115-121, 2017 | - |
dc.identifier.rimsid | 39069 | - |
dc.type.rims | ART | - |
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