Cited 19 times in
Long-Term Outcomes of NSAID-Induced Small Intestinal Injury Assessed by Capsule Endoscopy in Korea: A Nationwide Multicenter Retrospective Study
DC Field | Value | Language |
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dc.contributor.author | 천재희 | - |
dc.date.accessioned | 2018-03-26T17:09:26Z | - |
dc.date.available | 2018-03-26T17:09:26Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/157251 | - |
dc.description.abstract | BACKGROUND/AIMS: We evaluated the long-term outcome and clinical course of patients of nonsteroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by performing capsule endoscopy (CE). METHODS: A multicenter retrospective study was conducted using data collected from the CE nationwide database registry, which has been established since 2002. RESULTS: A total of 140 patients (87 males; mean age, 60.6±14.8 years) from the CE nationwide database registry (n=2,885) were diagnosed with NSAID-induced small intestinal injury and enrolled in our study. Forty-nine patients (35.0%) presented with a history of aspirin use and an additional 49 (35.0%) were taking NSAIDs without aspirin. The most prominent findings after performing CE were multiple ulcerations (n=82, 58.6%) and erosions or aphthae (n=32, 22.9%). During the follow-up period (mean, 15.9±19.0 months; range, 0 to 106 months), NSAID-induced small intestinal injury only recurred in six patients (4.3%). Older age and hypertension were positive predictive factors for recurrence. CONCLUSIONS: These results suggest that the recurrence of NSAID-induced small bowel injury was not frequent in the presence of conservative treatment. Therefore, the initial diagnosis using CE and the medication history are important. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Editorial Office of Gut and Liver | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Age Factors | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Anti-Inflammatory Agents, Non-Steroidal/adverse effects* | - |
dc.subject.MESH | Aspirin/adverse effects | - |
dc.subject.MESH | Capsule Endoscopy* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intestinal Diseases/chemically induced | - |
dc.subject.MESH | Intestinal Diseases/pathology* | - |
dc.subject.MESH | Intestine, Small/drug effects* | - |
dc.subject.MESH | Intestine, Small/injuries | - |
dc.subject.MESH | Intestine, Small/pathology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Ulcer/chemically induced | - |
dc.subject.MESH | Ulcer/pathology* | - |
dc.title | Long-Term Outcomes of NSAID-Induced Small Intestinal Injury Assessed by Capsule Endoscopy in Korea: A Nationwide Multicenter Retrospective Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Ki-Nam Shim | - |
dc.contributor.googleauthor | Eun Mi Song | - |
dc.contributor.googleauthor | Yoon Tae Jeen | - |
dc.contributor.googleauthor | Jin-Oh Kim | - |
dc.contributor.googleauthor | Seong Ran Jeon | - |
dc.contributor.googleauthor | Dong Kyung Chang | - |
dc.contributor.googleauthor | Hyun Joo Song | - |
dc.contributor.googleauthor | Yun Jeong Lim | - |
dc.contributor.googleauthor | Jin Soo Kim | - |
dc.contributor.googleauthor | Byong Duk Ye | - |
dc.contributor.googleauthor | Cheol Hee Park | - |
dc.contributor.googleauthor | Seong Woo Jeon | - |
dc.contributor.googleauthor | Jae Hee Cheon | - |
dc.contributor.googleauthor | Kwang Jae Lee | - |
dc.contributor.googleauthor | Ji Hyun Kim | - |
dc.contributor.googleauthor | Byung Ik Jang | - |
dc.contributor.googleauthor | Jeong Seop Moon | - |
dc.contributor.googleauthor | Hoon Jae Chun | - |
dc.contributor.googleauthor | Myung-Gyu Choi | - |
dc.identifier.doi | 10.5009/gnl14134 | - |
dc.contributor.localId | A04030 | - |
dc.relation.journalcode | J00954 | - |
dc.identifier.eissn | 2005-1212 | - |
dc.identifier.pmid | 25473079 | - |
dc.subject.keyword | Anti-inflammatory agents, non-steroidal | - |
dc.subject.keyword | Capsule endoscopy | - |
dc.subject.keyword | Outcome | - |
dc.contributor.alternativeName | Cheon, Jae Hee | - |
dc.contributor.affiliatedAuthor | Cheon, Jae Hee | - |
dc.citation.volume | 9 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 727 | - |
dc.citation.endPage | 733 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, Vol.9(6) : 727-733, 2015 | - |
dc.identifier.rimsid | 41811 | - |
dc.type.rims | ART | - |
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