Cited 5 times in
Serum interleukin-27 expression in patients with myasthenia gravis
DC Field | Value | Language |
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dc.contributor.author | 이정환 | - |
dc.contributor.author | 최영철 | - |
dc.date.accessioned | 2018-03-26T16:42:22Z | - |
dc.date.available | 2018-03-26T16:42:22Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0165-5728 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/156734 | - |
dc.description.abstract | Myasthenia gravis (MG)(1) is an autoimmune disease directed at the neuromuscular junction, and cytokines are thought to contribute to its immunopathogenesis. Interleukin-27 (IL-27)(2) plays a complex and pleiotropic role in immune responses associated with T helper cells. To assess the role of IL-27 in MG, we determined serum IL-27 levels in MG patients (n=32) compared to healthy controls (n=50). The median serum IL-27 level was significantly higher in MG patients (35.947pg/mL) than in controls (19.885pg/mL). Furthermore, serum IL-27 was significantly higher in early onset MG. This study suggests the possibility that IL-27 might contribute to MG pathogenesis or immunoregulation. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier/North-Holland | - |
dc.relation.isPartOf | JOURNAL OF NEUROIMMUNOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Interleukins/blood* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myasthenia Gravis/blood* | - |
dc.title | Serum interleukin-27 expression in patients with myasthenia gravis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Neurology | - |
dc.contributor.googleauthor | Ha-Neul Jeong | - |
dc.contributor.googleauthor | Jung Hwan Lee | - |
dc.contributor.googleauthor | Bum Chun Suh | - |
dc.contributor.googleauthor | Young-Chul Choi | - |
dc.identifier.doi | 10.1016/j.jneuroim.2015.09.010 | - |
dc.contributor.localId | A03133 | - |
dc.contributor.localId | A04116 | - |
dc.relation.journalcode | J01625 | - |
dc.identifier.eissn | 1872-8421 | - |
dc.identifier.pmid | 26531704 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S016557281530045X | - |
dc.subject.keyword | Interleukin-27 | - |
dc.subject.keyword | Myasthenia gravis | - |
dc.subject.keyword | Pathogenesis | - |
dc.contributor.alternativeName | Lee, Jung Hwan | - |
dc.contributor.alternativeName | Choi, Young Chul | - |
dc.contributor.affiliatedAuthor | Lee, Jung Hwan | - |
dc.contributor.affiliatedAuthor | Choi, Young Chul | - |
dc.citation.volume | 288 | - |
dc.citation.startPage | 120 | - |
dc.citation.endPage | 122 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NEUROIMMUNOLOGY, Vol.288 : 120-122, 2015 | - |
dc.identifier.rimsid | 39864 | - |
dc.type.rims | ART | - |
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