Cited 10 times in
A New Efficient Method for Detecting Phase Singularity in Cardiac Fibrillation
DC Field | Value | Language |
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dc.contributor.author | 박희남 | - |
dc.contributor.author | 정보영 | - |
dc.contributor.author | 임병현 | - |
dc.date.accessioned | 2017-10-26T07:56:58Z | - |
dc.date.available | 2017-10-26T07:56:58Z | - |
dc.date.issued | 2016 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/152729 | - |
dc.description.abstract | BACKGROUND: The point of phase singularity (PS) is considered to represent a spiral wave core or a rotor in cardiac fibrillation. Computational efficiency is important for detection of PS in clinical electrophysiology. We developed a novel algorithm for highly efficient and robust detection of PS. METHODS: In contrast to the conventional method, which calculates PS based on the line integral of the phase around a PS point equal to ±2π (the Iyer-Gray method), the proposed algorithm (the location-centric method) looks for the phase discontinuity point at which PS actually occurs. We tested the efficiency and robustness of these two methods in a two-dimensional mathematical model of atrial fibrillation (AF), with and without remodeling of ionic currents. RESULTS: 1. There was a significant association, in terms of the Hausdorff distance (3.30 ± 0.0 mm), between the PS points measured using the Iyer-Gray and location-centric methods, with almost identical PS trajectories generated by the two methods. 2. For the condition of electrical remodeling of AF (0.3 × ICaL), the PS points calculated by the two methods were satisfactorily co-localized (with the Hausdorff distance of 1.64 ± 0.09 mm). 3. The proposed location-centric method was substantially more efficient than the Iyer-Gray method, with a 28.6-fold and 28.2-fold shorter run times for the control and remodeling scenarios, respectively. CONCLUSION: We propose a new location-centric method for calculating PS, which is robust and more efficient compared with the conventionally used method. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/octet-stream | - |
dc.language | English | - |
dc.publisher | Public Library of Science | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | A New Efficient Method for Detecting Phase Singularity in Cardiac Fibrillation | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Young-Seon Lee | - |
dc.contributor.googleauthor | Jun-Seop Song | - |
dc.contributor.googleauthor | Minki Hwang | - |
dc.contributor.googleauthor | Byounghyun Lim | - |
dc.contributor.googleauthor | Boyoung Joung | - |
dc.contributor.googleauthor | Hui-Nam Pak | - |
dc.identifier.doi | 10.1371/journal.pone.0167567 | - |
dc.contributor.localId | A03609 | - |
dc.contributor.localId | A01776 | - |
dc.relation.journalcode | J02540 | - |
dc.identifier.eissn | 1932-6203 | - |
dc.identifier.pmid | 27907144 | - |
dc.contributor.alternativeName | Pak, Hui Nam | - |
dc.contributor.alternativeName | Joung, Bo Young | - |
dc.contributor.affiliatedAuthor | Joung, Bo Young | - |
dc.contributor.affiliatedAuthor | Pak, Hui Nam | - |
dc.citation.volume | 11 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | e0167567 | - |
dc.identifier.bibliographicCitation | PLOS ONE, Vol.11(12) : e0167567, 2016 | - |
dc.date.modified | 2017-10-24 | - |
dc.identifier.rimsid | 39737 | - |
dc.type.rims | ART | - |
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