Cited 7 times in
The Value of Elastic Modulus Index as a Novel Surrogate Marker for Cardiovascular Risk Stratification by Dimensional Speckle-Tracking Carotid Ultrasonography
DC Field | Value | Language |
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dc.contributor.author | 심지영 | - |
dc.contributor.author | 윤지현 | - |
dc.contributor.author | 장혁재 | - |
dc.contributor.author | 정남식 | - |
dc.contributor.author | 조인정 | - |
dc.contributor.author | 홍그루 | - |
dc.date.accessioned | 2017-10-26T07:47:57Z | - |
dc.date.available | 2017-10-26T07:47:57Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1975-4612 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/152523 | - |
dc.description.abstract | BACKGROUND: Carotid intima media thickness (CIMT) and the presence of carotid plaque have been used for risk stratification of cardiovascular disease (CVD). To date, however, the association between multi-directional functional properties of carotid artery and CVD has not been fully elucidated. We sought to explore the multi-directional mechanics of the carotid artery in relation to cardiovascular risk. METHODS: Four hundred one patients who underwent carotid ultrasound were enrolled between January 2010 and April 2013. A high risk of CVD was defined as more than 20% of 10-year risk based on the Framingham risk score. Using a speckle-tracking technique, the longitudinal and radial movements were analyzed in the B-mode images. Peak longitudinal and radial displacements, strain and strain rate were also measured. Beta stiffness and elastic modulus index were calculated from the radial measurements. RESULTS: Of the overall sample, 13% (52) of patients comprised the high-risk group. In multivariate logistic regression, CIMT and elastic modulus index were independently associated with a high-risk of CVD {odds ratio (OR): 1.810 [95% confidence interval (CI) 1.249-2.622] and OR: 1.767 (95% CI: 1.177-2.652); p = 0.002, 0.006, respectively}. The combination of CIMT and elastic modulus index correlated with a high-risk of CVD more so than CIMT alone. CONCLUSION: The elastic modulus index of the carotid artery might serve as a novel surrogate marker of high-risk CVD. Measurement of the multi-directional mechanics of the carotid artery using the speckle tracking technique has potential for providing further information over conventional B-mode ultrasound for stratification of CVD risk. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean, English | - |
dc.publisher | Korean Society of Echocardiography | - |
dc.relation.isPartOf | Journal of Cardiovascular Ultrasound | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | The Value of Elastic Modulus Index as a Novel Surrogate Marker for Cardiovascular Risk Stratification by Dimensional Speckle-Tracking Carotid Ultrasonography | - |
dc.type | Article | - |
dc.publisher.location | Korea | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Ji Hyun Yoon | - |
dc.contributor.googleauthor | In-Jeong Cho | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.contributor.googleauthor | Ji Min Sung | - |
dc.contributor.googleauthor | Jinyong Lee | - |
dc.contributor.googleauthor | Hojin Ryoo | - |
dc.contributor.googleauthor | Chi Young Shim | - |
dc.contributor.googleauthor | Geu-Ru Hong | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.identifier.doi | 10.4250/jcu.2016.24.3.215 | - |
dc.contributor.localId | A02609 | - |
dc.contributor.localId | A03490 | - |
dc.contributor.localId | A03585 | - |
dc.contributor.localId | A03892 | - |
dc.contributor.localId | A04386 | - |
dc.contributor.localId | A02213 | - |
dc.relation.journalcode | J01298 | - |
dc.relation.journalsince | 2006~ | - |
dc.identifier.pmid | 27721952 | - |
dc.relation.journalbefore | ~2005 Journal of the Korean Society of Echocardiography (한국심초음파학회지) | - |
dc.subject.keyword | Cardiovascular disease | - |
dc.subject.keyword | Carotid artery | - |
dc.subject.keyword | Elastic modulus | - |
dc.contributor.alternativeName | Shim, Chi Young | - |
dc.contributor.alternativeName | Yoon, Ji Hyun | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.alternativeName | Cho, In Jeong | - |
dc.contributor.alternativeName | Hong, Geu Ru | - |
dc.contributor.affiliatedAuthor | Yoon, Ji Hyun | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Cho, In Jeong | - |
dc.contributor.affiliatedAuthor | Hong, Geu Ru | - |
dc.contributor.affiliatedAuthor | Shim, Chi Young | - |
dc.citation.volume | 24 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 215 | - |
dc.citation.endPage | 222 | - |
dc.identifier.bibliographicCitation | Journal of Cardiovascular Ultrasound, Vol.24(3) : 215-222, 2016 | - |
dc.date.modified | 2017-10-24 | - |
dc.identifier.rimsid | 48726 | - |
dc.type.rims | ART | - |
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