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건강한 성인에서 혈중 DHEA-s 농도와 TAS의 관련성
DC Field | Value | Language |
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dc.contributor.author | 이덕철 | - |
dc.contributor.author | 이혜리 | - |
dc.date.accessioned | 2017-10-26T06:30:28Z | - |
dc.date.available | 2017-10-26T06:30:28Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 2005-6443 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/150892 | - |
dc.description.abstract | Background : DHEA is the most abundant steroid hormone secreted from the adrenal cortex and has several roles such as increasing insulin sensitivity, lowering serum lipid, improving obesity, and anti-cancer effects. DHEA levels vary profoundly and levels decline as age increases. But the role of DHEA in the aging process is not yet fully understood. Total antioxidant status(TAS) which provides information of one's antioxidant capacity, also decreases with age. In this study, we investigated the relationship between TAS and serum DHEA-s concentration. Methods : By reviewing the medical records of 197 healthy adults, we determined the serum levels of DHEA-s and TAS according to BMI, pulse pressure, WBC, hs-CRP, A/G ratio, LDL-cholesterol, triglyceride, ferritin, uric acid and total bilirubin. We studied the relationship between the parameters by Pearson correlation coefficients and multiple regression analysis. Results : The mean level for TAS and serum DHEA-s was 1.20 mml/L and 177.3 ug/mL, respectively. Serum DHEA-s correlated positively with TAS (r=0.44) and negatively for age (r=-0.44). WBC, triglyceride and uric acid also showed statistically significant correlations. But, according to multiple regression analysis DHEA-s only correlated with TAS and age. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean | - |
dc.publisher | 대한가정의학회 | - |
dc.relation.isPartOf | Journal of the Korean Academy of Family Medicine (가정의학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | DHEA | - |
dc.subject.MESH | TAS | - |
dc.title | 건강한 성인에서 혈중 DHEA-s 농도와 TAS의 관련성 | - |
dc.title.alternative | The Relation between Serum DHEA-s Level and TAS in Healthy Adults | - |
dc.type | Article | - |
dc.publisher.location | Korea | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | 이혜리 | - |
dc.contributor.googleauthor | 정동혁 | - |
dc.contributor.googleauthor | 임지애 | - |
dc.contributor.googleauthor | 김경철 | - |
dc.contributor.googleauthor | 이덕철 | - |
dc.contributor.localId | A02716 | - |
dc.contributor.localId | A03310 | - |
dc.relation.journalcode | J03700 | - |
dc.identifier.eissn | 2092-6715 | - |
dc.subject.keyword | DHEA | - |
dc.subject.keyword | TAS | - |
dc.contributor.alternativeName | Lee, Duk Chul | - |
dc.contributor.alternativeName | Lee, Hye Ree | - |
dc.citation.volume | 26 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 26 | - |
dc.citation.endPage | 31 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Academy of Family Medicine (가정의학회지), Vol.26(4) : 26-31, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 42736 | - |
dc.type.rims | ART | - |
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