Cited 187 times in
Improvement in preoperative staging of gastric adenocarcinoma with positron emission tomography
DC Field | Value | Language |
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dc.contributor.author | 김준억 | - |
dc.contributor.author | 노성훈 | - |
dc.contributor.author | 윤미진 | - |
dc.contributor.author | 임준석 | - |
dc.contributor.author | 정재호 | - |
dc.contributor.author | 형우진 | - |
dc.date.accessioned | 2017-10-26T06:15:37Z | - |
dc.date.available | 2017-10-26T06:15:37Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0008-543X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/150721 | - |
dc.description.abstract | BACKGROUND: Positron emission tomography (PET) with 18- fluorodeoxyglucose (FDG) has been used to both detect and stage a variety of malignancies. The current study examined the value of PET for preoperative staging of gastric adenocarcinoma. METHODS: Sixty-eight patients (49 males and 19 females) with gastric adenocarcinoma, who were referred for preoperative FDG-PET scans, were enrolled in this study. The patients underwent spiral-computed tomography (CT) within 1 week of referral. The final diagnosis in all patients was made by histologic and surgical findings. For quantitative PET analysis, the regional tumor FDG uptake was measured by the standardized uptake value (SUV). RESULTS: For the primary tumor of a gastric adenocarcinoma, PET demonstrated an increased uptake in 64 of 68 patients (sensitivity, 94%), with a mean SUV of 7.0 (range, 0.9-27.7). A comparison of FDG uptake and clinicopathologic features showed significant association between FDG uptake and macroscopic type, tumor size, lymph node metastasis, histologic type, and TNM stage. The PET scan had a similar accuracy with that of CT for diagnosing local and distant lymph node metastases as well as peritoneal status. In assessing local lymph node status, however, PET had a higher specificity than CT (92% vs. 62%, P = 0.000). Moreover, PET had additional diagnostic value in 10 (15%) of 68 patients by upstaging 4 (6%) and downstaging 6 (9%) patients. PET combined with CT was more accurate for preoperative staging than either modality alone (66% vs. 51%, 66% vs. 47%, respectively; P = 0.002). CONCLUSIONS: FDG-PET improves the preoperative TNM staging of gastric adenocarcinoma. Based on its superior specificity, FDG-PET can facilitate the selection of patients for a curative resection by confirming a nodal status identified by CT. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Wiley | - |
dc.relation.isPartOf | CANCER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma/diagnostic imaging* | - |
dc.subject.MESH | Adenocarcinoma/secondary | - |
dc.subject.MESH | Adenocarcinoma/surgery | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Carcinoma, Signet Ring Cell/diagnostic imaging | - |
dc.subject.MESH | Carcinoma, Signet Ring Cell/secondary | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorodeoxyglucose F18 | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lymph Nodes/pathology | - |
dc.subject.MESH | Lymphatic Metastasis/pathology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Peritoneal Neoplasms/diagnostic imaging | - |
dc.subject.MESH | Peritoneal Neoplasms/secondary | - |
dc.subject.MESH | Positron-Emission Tomography | - |
dc.subject.MESH | Preoperative Care | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Radiography | - |
dc.subject.MESH | Radiopharmaceuticals | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Stomach Neoplasms/diagnostic imaging* | - |
dc.subject.MESH | Stomach Neoplasms/surgery | - |
dc.title | Improvement in preoperative staging of gastric adenocarcinoma with positron emission tomography | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.department | Dept. of Nuclear Medicine (핵의학교실) | - |
dc.contributor.department | Dept. of Radiology (영상의학교실) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Jian Chen | - |
dc.contributor.googleauthor | Jae-Ho Cheong | - |
dc.contributor.googleauthor | Mi Jin Yun | - |
dc.contributor.googleauthor | Junuk Kim | - |
dc.contributor.googleauthor | Joon Seok Lim | - |
dc.contributor.googleauthor | Woo Jin Hyung | - |
dc.contributor.googleauthor | Sung Hoon Noh | - |
dc.identifier.doi | 10.1002/cncr.21074 | - |
dc.contributor.localId | A00954 | - |
dc.contributor.localId | A01281 | - |
dc.contributor.localId | A02550 | - |
dc.contributor.localId | A03408 | - |
dc.contributor.localId | A03717 | - |
dc.contributor.localId | A04382 | - |
dc.relation.journalcode | J00434 | - |
dc.identifier.eissn | 1097-0142 | - |
dc.identifier.pmid | 15856477 | - |
dc.subject.keyword | gastric adenocarcinoma | - |
dc.subject.keyword | positron emission tomography | - |
dc.subject.keyword | computed tomography | - |
dc.subject.keyword | TNM staging | - |
dc.contributor.alternativeName | Kim, Junuk | - |
dc.contributor.alternativeName | Noh, Sung Hoon | - |
dc.contributor.alternativeName | Yun, Mi Jin | - |
dc.contributor.alternativeName | Lim, Joon Seok | - |
dc.contributor.alternativeName | Cheong, Jae Ho | - |
dc.contributor.alternativeName | Hyung, Woo Jin | - |
dc.citation.volume | 103 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 2383 | - |
dc.citation.endPage | 2390 | - |
dc.identifier.bibliographicCitation | CANCER, Vol.103(11) : 2383-2390, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 44235 | - |
dc.type.rims | ART | - |
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