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Optic Nerve Head Topographic Measurements and Retinal Nerve Fiber Layer Thickness in Physiologic Large Cups

Authors
 Kyung Hyup Min  ;  Gong Je Seong  ;  Young Jae Hong  ;  Chan Yun Kim 
Citation
 Korean Journal of Ophthalmology, Vol.19(3) : 189-194, 2005 
Journal Title
Korean Journal of Ophthalmology
ISSN
 1011-8942 
Issue Date
2005
MeSH
Adolescent ; Adult ; Glaucoma/pathology* ; Humans ; Middle Aged ; Nerve Fibers/pathology* ; Optic Disk/pathology* ; Retina/pathology*
Keywords
HRT ; OCT ; Optic nerve head ; Physiologic large cups ; Retinal nerve fiber layer ; Rim area ; Rim volume
Abstract
PURPOSE: To evaluate the parameters of optic nerve head (ONH) and retinal nerve fiber layer (RNFL) in patients with large cup/disc ratio (CDR) and normal neuroretinal rim configuration who have normal perimetry (physiologic large cups, LC) and to compare these parameters with those of the normal and early glaucoma patients.
METHODS: Using Heidelberg retinal tomography (HRT) and optical coherence tomography (OCT), 30 patients with LC, 29 normal subjects, and 31 early glaucoma patients were examined. One eye from each subject was randomly selected.
RESULTS: Significant differences between LC and glaucomatous eyes (GE) were found in parameters indicating loss of nerve fibers, such as rim area, rim volume, and mean RNFL thickness. However, there was no difference between LC and normal eyes (NE) in RNFL thickness, rim area, and rim volume. LC was able to be defined as a normal central excavation with a large disc and large CDR with a normal rim area.
CONCLUSIONS: HRT ONH parameters and RNFL thickness obtained with OCT may be useful for differentiating between glaucoma and LC eyes.
Files in This Item:
T200500371.pdf Download
DOI
10.3341/kjo.2005.19.3.189
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chan Yun(김찬윤) ORCID logo https://orcid.org/0000-0002-8373-9999
Seong, Gong Je(성공제) ORCID logo https://orcid.org/0000-0002-5456-4296
Hong, Young Jae(홍영재)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147583
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