Cited 4 times in
Anti-Vascular Endothelial Growth Factor with Gas for Submacular Hemorrhage
DC Field | Value | Language |
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dc.contributor.author | 변석호 | - |
dc.date.accessioned | 2017-02-27T08:00:57Z | - |
dc.date.available | 2017-02-27T08:00:57Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1040-5488 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/147055 | - |
dc.description.abstract | PURPOSE: To investigate the treatment outcome of pneumatic displacement and intravitreal anti-vascular endothelial growth factor (VEGF) for submacular hemorrhage (SMH) from exudative age-related macular degeneration (AMD). METHODS: Best-corrected visual acuity (BCVA) and central foveal thickness (CFT) were measured at baseline and at 1, 3, and 6 months after initial treatment in 72 eyes of 72 patients treated with a combination of pneumatic displacement and anti-VEGF injection for SMH from exudative AMD. RESULTS: Best-corrected visual acuity and CFT showed significant improvement from baseline during the 6-month follow-up period (logarithm of the minimum angle of resolution BCVA from 1.80 to 1.00, CFT from 886 to 383 μm, p < 0.001, respectively). The decrease in subretinal hemorrhage was greater than that in subretinal pigment epithelial hemorrhage at 1 month after initial treatment (p < 0.001). In eyes with symptoms for less than 30 days, higher reflectivity of hemorrhage on optical coherence tomography and higher CFT were associated with lower BCVA after 6 months of treatment (reflectivity B = 0.335, p = 0.007; CFT B = 0.001, p = 0.003). CONCLUSIONS: The combination of pneumatic displacement and intravitreal anti-VEGF is a useful treatment option for SMH secondary to AMD. Higher baseline CFT and higher reflectivity of hemorrhage were associated with lower BCVA 6 months after initial treatment. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.format.extent | 173~180 | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | OPTOMETRY AND VISION SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Angiogenesis Inhibitors/therapeutic use* | - |
dc.subject.MESH | Bevacizumab/therapeutic use | - |
dc.subject.MESH | Combined Modality Therapy | - |
dc.subject.MESH | Endotamponade* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorescein Angiography | - |
dc.subject.MESH | Fluorocarbons/administration & dosage* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intravitreal Injections | - |
dc.subject.MESH | Macular Degeneration/complications | - |
dc.subject.MESH | Macular Degeneration/diagnosis | - |
dc.subject.MESH | Macular Degeneration/therapy* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Ranibizumab/therapeutic use | - |
dc.subject.MESH | Retinal Hemorrhage/diagnosis | - |
dc.subject.MESH | Retinal Hemorrhage/etiology | - |
dc.subject.MESH | Retinal Hemorrhage/therapy* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Sulfur Hexafluoride/administration & dosage* | - |
dc.subject.MESH | Tomography, Optical Coherence | - |
dc.subject.MESH | Vascular Endothelial Growth Factor A/antagonists & inhibitors* | - |
dc.subject.MESH | Visual Acuity | - |
dc.title | Anti-Vascular Endothelial Growth Factor with Gas for Submacular Hemorrhage | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Ophthalmology | - |
dc.contributor.googleauthor | Joo Youn Shin | - |
dc.contributor.googleauthor | Hun Jin Choi | - |
dc.contributor.googleauthor | Byunghoon Chung | - |
dc.contributor.googleauthor | Moonjung Choi | - |
dc.contributor.googleauthor | Jonghyun Lee | - |
dc.contributor.googleauthor | Suk Ho Byeon | - |
dc.identifier.doi | 10.1097/OPX.0000000000000777 | - |
dc.contributor.localId | A01849 | - |
dc.relation.journalcode | J02437 | - |
dc.identifier.eissn | 1538-9235 | - |
dc.identifier.pmid | 26704146 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00006324-201602000-00010&LSLINK=80&D=ovft | - |
dc.subject.keyword | anti-vascular endothelial growth factor | - |
dc.subject.keyword | age-related macular degeneration | - |
dc.subject.keyword | choroidal neovascularization | - |
dc.subject.keyword | polypoidal choroidal vasculopathy | - |
dc.subject.keyword | submacular hemorrhage | - |
dc.contributor.alternativeName | Byeon, Suk Ho | - |
dc.contributor.affiliatedAuthor | Byeon, Suk Ho | - |
dc.citation.volume | 93 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 173 | - |
dc.citation.endPage | 180 | - |
dc.identifier.bibliographicCitation | OPTOMETRY AND VISION SCIENCE, Vol.93(2) : 173-180, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47087 | - |
dc.type.rims | ART | - |
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