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Amoxicillin-Sulbactam (Sultamox)의 주요 임상 분리세균에 대한 시험관내 항균력
DC Field | Value | Language |
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dc.contributor.author | 용동은 | - |
dc.contributor.author | 이경원 | - |
dc.date.accessioned | 2016-05-16T11:16:15Z | - |
dc.date.available | 2016-05-16T11:16:15Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 1225-7850 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/144174 | - |
dc.description.abstract | Background : Q-lactam antibiotics are one of the most frequently used antimicrobial agents. However, with the increase of a-lactamase-producing bacteria, penicillins and amoxicillin have become less useful. Amoxici Ili n-sulbactam (AXS) was developed to restore the activity. The aim of this study was to determine the in vitro activities of AXS against recent clinical isolates. Methods : Various aerobic bacteria tested were isolated from clinical specimens in Severance Hospital during . 2000 to 2001 Antimicrobial susceptibility was determined by the NCCLS agar dilution method. Results : Oxacillin-susceptible Staphylococcus aureus and coagulase-negative Staphylococcus I Streptococcus pneumoniae and S. pyogenes were susceptible to ampicillin-sulbactam (APS), amoxicillin-clavulanic acid (AXC) and AXS. For Moraxella (Branhamella) catarrhalis and Haemophilus influenzae, MIC9os of APS, AXC and AXS were 0.5 ug/"mL and´ 8 ug/mL, respectively, which were 16-fold lower than those of amoxicillin. For Klebsiella oxytoca and Proteus mirabilis, MIC90 of amoxicillin was >128 Pg/mL, but M1Cgos of APS, AXC and AXS were 8-32 ug/mL and 4-16 ug/mL, respectively. Conclusion : AXS showed good antimicrobial activities against oxacilli n- susceptible Staphylococcus, M. (B.) catarrhalis, H. influenzae, K oxytoca, and P. mirabilis. Therefore, It would be useful for the treatment of infections due to these organisms. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 203~212 | - |
dc.relation.isPartOf | Journal of the Korean Society for Chemotherapy (대한화학요법학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Amoxicillin-Sulbactam (Sultamox)의 주요 임상 분리세균에 대한 시험관내 항균력 | - |
dc.title.alternative | In Vitro Activities of Amoxicillin-Sulbactam (Sultamox) against Major Clinical Isolates of Bacteria | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | 염종화 | - |
dc.contributor.googleauthor | 용동은 | - |
dc.contributor.googleauthor | 김명숙 | - |
dc.contributor.googleauthor | 이경원 | - |
dc.contributor.googleauthor | 정윤섭 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02423 | - |
dc.contributor.localId | A02649 | - |
dc.relation.journalcode | J01850 | - |
dc.contributor.alternativeName | Yong, Dong Eun | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.contributor.affiliatedAuthor | Yong, Dong Eun | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Won | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 20 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 203 | - |
dc.citation.endPage | 212 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Society for Chemotherapy (대한화학요법학회지), Vol.20(3) : 203-212, 2002 | - |
dc.identifier.rimsid | 56658 | - |
dc.type.rims | ART | - |
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