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인슐린저항성과 관상동맥질환의 중증도와의 관계
DC Field | Value | Language |
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dc.contributor.author | 안철우 | - |
dc.contributor.author | 차봉수 | - |
dc.date.accessioned | 2016-05-16T11:07:37Z | - |
dc.date.available | 2016-05-16T11:07:37Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 1015-6461 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/143846 | - |
dc.description.abstract | Background: Insulin resistance (IR) has been identified as a risk factor of atherosclerosis, which may be induced through a mechanism brought about by hypertension, obesity, glucose intolerance and dyslipidemia. The purpose of this study was to investigate the relationship between coronary artery disease (CAD) and insulin resistance. Methods: Of 92 subjects having undergone coronary angiography 70 with significantly stenotic coronary artery were designated as the CAD group, with the other 22, without stenosis, as the control group. The CAD group was subdivided into 3 smaller groups according to the severity of their CAD; these being 1-vessel disease (group 1, n=31), 2-vessel disease (group 2, n=25), and 3-vessel disease (group 3, n=14). Results: Kitt for patients with CAD was significantly lower than in the control group, and also for those in group 1 compared to groups 2 and 3, 2.72+/-1.29, 2.25+/-0.68 and 2.21+/-0.78%/min, with that of the controls being 3.01+/-1.22%/min p<0.05). There were significant differences between the IR group and the non-IR group in the common carotid artery intima-media thickness (1.09mm vs. 0.87mm, p<0.05), the waist-hip ratio (1.09 vs. 0.93, p<0.05) and the body fat contents (32% vs. 27%, p<0.05).Insulin resistance was assessed by the short insulin tolerance test, and the insulin resistance (IR) group was defined as having a Kitt less than 2.5%/min. Conclusion: These results suggest that insulin resistance is an important risk factor for CAD, and is related to the severity of coronary atherosclerosis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 169~178 | - |
dc.relation.isPartOf | Journal of Korean Diabetes Association (당뇨병) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 인슐린저항성과 관상동맥질환의 중증도와의 관계 | - |
dc.title.alternative | Insulin Resistance and severity of coronary artery diseases in Patients with Coronary Artery Diseases | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | 김대중 | - |
dc.contributor.googleauthor | 남재현 | - |
dc.contributor.googleauthor | 최동훈 | - |
dc.contributor.googleauthor | 김형진 | - |
dc.contributor.googleauthor | 김수경 | - |
dc.contributor.googleauthor | 김세화 | - |
dc.contributor.googleauthor | 이유미 | - |
dc.contributor.googleauthor | 안철우 | - |
dc.contributor.googleauthor | 차봉수 | - |
dc.contributor.googleauthor | 송영득 | - |
dc.contributor.googleauthor | 임승길 | - |
dc.contributor.googleauthor | 김경래 | - |
dc.contributor.googleauthor | 이현철 | - |
dc.contributor.googleauthor | 허갑범 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02270 | - |
dc.contributor.localId | A03996 | - |
dc.relation.journalcode | J01508 | - |
dc.subject.keyword | Insulin resistance | - |
dc.subject.keyword | Short insulin tolerance test | - |
dc.subject.keyword | Coronary artery disease | - |
dc.subject.keyword | Atherosclerosis | - |
dc.subject.keyword | Coronary angiography | - |
dc.contributor.alternativeName | Ahn, Chul Woo | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Ahn, Chul Woo | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 26 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 169 | - |
dc.citation.endPage | 178 | - |
dc.identifier.bibliographicCitation | Journal of Korean Diabetes Association (당뇨병), Vol.26(3) : 169-178, 2002 | - |
dc.identifier.rimsid | 37601 | - |
dc.type.rims | ART | - |
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