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Effect of Botulinum Toxin A Chemodnervation in Sensory Strabismus
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이종복 | - |
dc.date.accessioned | 2016-02-19T11:17:28Z | - |
dc.date.available | 2016-02-19T11:17:28Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 0191-3913 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/142819 | - |
dc.description.abstract | To study the effect of botulinum toxin type A chemodenervation in sensory strabismus. Twelve patients with sensory strabismus were treated with an injection of botulinum toxin type A (Botox; Allergan, Irvine, Calif). Botulinum toxin type A was diluted with 0.9% sodium chloride without preservative at a dose that ranged from 1.25-5 U. A Teflon-coated needle electrode was inserted into the medial rectus muscle in cases of esotropia and into the lateral rectus muscle in cases of exotropia. Four patients were treated with > or =2 injections of botulinum toxin type A. Changes in the angle of strabismus and related complications were followed for >6 months postinjection. The mean deviation before injection was 33.8 prism diopters (delta) and the mean corrective effect on the deviation was 72.8% after injection in patients with sensory strabismus. The final deviation in 9 patients was <10 delta. Complications were hypertropia in 3 (25%) patients and conjunctival hemorrhage in 1 (8.3%) patient. Botulinum toxin type A is likely to prevent muscle contracture and affect muscle and neuronal tissues. This study on the effects of sensory strabismus with botulinum toxin type A injection suggests it has the potential to replace surgery or be used as an adjuvant therapy. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 68~71 | - |
dc.relation.isPartOf | JOURNAL OF PEDIATRIC OPHTHALMOLOGY & STRABISMUS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Botulinum Toxins, Type A* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Muscle Denervation/methods* | - |
dc.subject.MESH | Neuromuscular Agents* | - |
dc.subject.MESH | Oculomotor Muscles/innervation* | - |
dc.subject.MESH | Strabismus/therapy* | - |
dc.subject.MESH | Sympathectomy, Chemical/methods* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Vision, Binocular | - |
dc.title | Effect of Botulinum Toxin A Chemodnervation in Sensory Strabismus | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Han | - |
dc.contributor.googleauthor | Sueng Han | - |
dc.contributor.googleauthor | Lew | - |
dc.contributor.googleauthor | Helen | - |
dc.contributor.googleauthor | Jeong | - |
dc.contributor.googleauthor | Chang Woog | - |
dc.contributor.googleauthor | Lee | - |
dc.contributor.googleauthor | Jong Bok | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03140 | - |
dc.relation.journalcode | J01685 | - |
dc.identifier.eissn | 1938-2405 | - |
dc.identifier.pmid | 11310709 | - |
dc.identifier.url | http://search.proquest.com/docview/222170489?accountid=131089 | - |
dc.contributor.alternativeName | Lee, Jong Bok | - |
dc.contributor.affiliatedAuthor | Lee, Jong Bok | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 38 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 68 | - |
dc.citation.endPage | 71 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PEDIATRIC OPHTHALMOLOGY & STRABISMUS, Vol.38(2) : 68-71, 2001 | - |
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