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발병 연령에 따른 궤양성 대장염의 임상적 특성

Title
 발병 연령에 따른 궤양성 대장염의 임상적 특성
Other Titles
 Characteristics of Ulcerative Colitis According to the Age of Onset
Authors
 이충렬; 서정훈; 김원호; 최창환; 이재훈; 이현웅; 정혜원; 한창훈
Issue Date
2001
Journal Title
 Korean Journal of Gastroenterology (대한소화기학회지)
ISSN
 0301-2883
Citation
 Korean Journal of Gastroenterology (대한소화기학회지), Vol.37(3) : 196~202, 2001
Abstract
Background/Aims: Ulcerative colitis(UC) exhibits a bimodality in age-specific incidence rates, with a first peak in the young age and a second peak in the old age. We attempted to determine whether UC actually behaves differently in the elderly compared with the young. Methods: Patients with UC were divided into two groups (early vs. late onset) by the onset age of 40. Results: Incidence rate reached a peak in the forth decade in female patients, whereas it showed a bimodal age distribution with a first peak in the third decade and a second peak in fifth decade in male patients. Symptom duration before diagnosis was longer in the patients with late-onset UC than in the patients with early-onset UC (p value<0.05). There were no significant differences in the extent of lesion, the positive rate of serum anti-neutrophil cytoplasmic antibody, the disease activity, the frequency of admission, the use of steroid, and concern about the disease between the patients with early and late-onset UC. Conclusions: Age and sex distribution in this study were similar to those in other countries, and a bimodal age distribution was noted in males. The late-onset patients had longer duration from the onset of symptoms to diagnosis than the early-onset patients. However, there was no significant difference in clinical characteristics between the patients with early-onset UC and the patients with late-onset UC.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/142775
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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