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새로운 항정신병약물 : 세로토닌 및 글루타메이트 수용체 관련 약물들

Other Titles
 Newer Antipsychotics : Serotonin and Glutamate Receptor Related Drugs 
Authors
 김찬형 
Citation
 Korean Journal of Psychopharmacology (대한정신약물학회지), Vol.12(2) : 115~123, 2001 
Journal Title
 Korean Journal of Psychopharmacology (대한정신약물학회지) 
ISSN
 1017-5717 
Issue Date
2001
Abstract
Several decades of research attempting to explain schizophrenia regarding dopamine hyperactivity hypothesis have produced disappointing results. New hypotheses focusing on serotonin-dopamine interactions and hypofunction of the NMDA glutamate transmitter system have been emerging as potentially more promising concepts. The next generation of treatments for schizophrenia, whether they are based on dopamine, serotonin, or glutamate etc., should be effective on negative symptoms and cognitive deficits as well as positive symptoms. In this article, I review the brief overview of these hypotheses and new drugs based on the hypotheses.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/142759
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Psychiatry
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