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관상동맥질환 위험요인 구명을 위한 코호트내 환자-대조군 연구

Title
 관상동맥질환 위험요인 구명을 위한 코호트내 환자-대조군 연구 
Other Titles
 A Nested Case Control Study on Risk Factors for Coronary Heart Disease in Korean 
Authors
 김기순 ; 박종 ; 류소연 ; 서일 ; 지선하 ; 고광욱 ; 이덕희 ; 이강숙 ; 이태용 ; 천병렬 ; 김춘배 ; 박종구 
Issue Date
2001
Journal Title
 Korean Journal of Preventive Medicine (예방의학회지) 
ISSN
 2545-5985 
Citation
 Korean Journal of Preventive Medicine (예방의학회지), Vol.34(2) : 149~156, 2001 
Abstract
Objective : To elucidate risk factors for coronary heart diseases among Korean males. Methods : A nested case control study was conducted among a Korea Medical Insurance Cooperation(KMIC) cohort composed of 108,802 males. The eases included 246 male patients who were admitted to hospital due to coronary heart diseases from 1993 to 1997 (120-25 by ICD) and whose diagnosis was confirmed by the protocol by WHO MONICA Project(1994). The control group was composed of 483 patients selected by frequency matching considering age and resident area from an inpatient care group without coronary heart disease during the same period. For study cases and the controls, the results of a health check-up in 1990 and a questionnaire on life style in 1992 were received through the KMIC. Some additional information was collected by telephone interviews during October 1999. Results : Multiple logistic regression analysis showed that the odds ratio(OR) of coronary heart diseases among past smokers and current smokers as compared to non-smokers were 1.94(95% CI : 1.14-3.31) and 2.20(55% CI : 1.35-3.59), respectively. The OR among persons who drank 4 cups or more of caffeinated beverages such as coffee or tea daily as compared to persons who drank one cup for 2-3 days was 2.50(95% CI : 1.07-6.12). The OR among persons with high normal BP and stage 3 hypertension against normotension were 2.51 (95% CI : 1.44-4.37) and 5.08(95% CI : 2.38-10.84). The OR among persons whose blood cholesterol were 240 mg/dL or mere against lower than 200mg/dL was 2.24(95% CI : 1.43-3.49). Conclusion : Smoking, drinking of excessive caffeinated beverages, hypertension and high blood cholesterol were proven to be significant risk factors for coronary heart diseases among Korean males.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/142728
Appears in Collections:
1. 연구논문 > 4. Graduate School of Public Health > Graduate School of Public Health
1. 연구논문 > 1. College of Medicine > Dept. of Preventive Medicine
Yonsei Authors
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