Cited 0 times in

27 9

Penicillin 내성 폐렴구균 감염의 치료 성적

Other Titles
 Treatment Outcome of Penicillin-resistant S. Pneumoniae Infection 
Authors
 이경원 
Citation
 Korean Journal of Pediatrics (소아과), Vol.44(2) : 149~153, 2001 
Journal Title
 Korean Journal of Pediatrics (소아과) 
ISSN
 1738-1061 
Issue Date
2001
Abstract
Purpose: Streptococcus pneumoniae is a normal flora and common pathogen of the upper respiratory tract. S. pneumoniae infections are estimated to cause not only localized infection such as pneumonia, and otitis media, but also systemic infections, for example meningitis, sepsis, and so on. Recently, the resistance of S. pneumoniae to penicillin and multidrug has been rapidly increasing in many other parts of the world. So strategies for treating S. pneumoniae are of concern. In this article, we reviewed the efficacy of antibiotics against multidrug-resistant S. pneumoniae infection in childhood. Methods: Medical records of children who had infections from penicillin-resistant S. pneumoniae admitted to Severance Hospital between January 1997 and December 1998 were reviewed. The patients with congenital heart disease or malignancies were excluded to rule out other factors except antibiotics. We reviewed the efficacy of antibiotics, loss of fever, and duration of improvement of the general conditi. Results: The median age of children was four years old. There were 20 cases of localized infections such as pneumonia, otitis media(66.7%), and 10 cases of systemic infections such as meningitis, sepsis(33.4%). Sixty three % of patients were treated with penicillin, thirteen % with 3rd cephalosporin, and twenty three % with vancomycin. Stastically no significant difference was found between these three groups(P=0.85). Conclusion: In this study, antibiotics didn't significantly influence the treatment of multidrug- resistant S. pneumoniae infections. The treatment of many patients with congenital heart disease or malignancies was complicated. This suggests that general conditions of patients, such as immunity, is more important than antibiotics in treating the multidrug-resistant S. pneumoniae infection.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/142316
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Laboratory Medicine
Yonsei Authors
사서에게 알리기
  feedback
Files in This Item:
T200102002.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse