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세포생물학과 Proteomics 응용

Other Titles
 Proteomic application in cell biology (review). 
Authors
 김동욱 
Citation
 Korean Journal of Microbiololgy, Vol.37(2) : 109~113, 2001 
Journal Title
 Korean Journal of Microbiololgy 
ISSN
 0440-2413 
Issue Date
2001
Abstract
As the complete genomic sequences accumulate, the use of global techniques became possible. DNA microarray is a powerful technology for measuring global mRNA levels. This method, however, does not provide information on post-translational modifications of proteins. In addition, mRNA levels do not strictly correlate with protein concentrations, especially for lower-abundance proteins. Therefore, studies at the level of transcription are not sufficient to understand cellular activity. Proteomic techniques to analyze protein expression and function at the large-scale have been developed and used. This review introduces a simple explanation for proteomic analysis and examples of how proteomics is applied in cell biology.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/142027
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Physiology
Yonsei Authors
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