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Correlation of vestibular aqueduct size with air-bone gap in enlarged vestibular aqueduct syndrome

Title
 Correlation of vestibular aqueduct size with air-bone gap in enlarged vestibular aqueduct syndrome
Authors
 Young Joon Seo; Jinna Kim; Jae Young Choi
Issue Date
2015
Journal Title
 Laryngoscope
ISSN
 0023-852X
Citation
 Laryngoscope, Vol.null(null) : null, 2015
Abstract
OBJECTIVES/HYPOTHESIS: Patients with enlarged vestibular aqueduct (EVA) often demonstrate an air-bone gap (ABG) at low frequencies on audiometric testing. The mechanism for this has not been well elucidated. We investigated vestibular aqueduct (VA) size and ABG in patients with EVA, and assessed the relationship between VA diameter and ABG. STUDY DESIGN: Retrospective review. METHODS: We assessed 98 ears from 49 individuals diagnosed with Pendred syndrome. The VA diameters of ears in groups with (n = 60) and without (n = 38) ABG were measured using axial computed tomography images. Three different parameters of VA diameter (fundus, midpoint, and porous width) were correlated with the results of pure tone analysis. RESULTS: We found that patients with ABG have larger diameters of the VA than patients without ABG (fundus width = 1.13 vs. 0.71 mm, respectively; midpoint width = 3.23 vs. 2.77 mm, respectively; porous width = 2.73 vs. 2.29 mm, respectively; P < .001, .038, and .049, respectively). A cutoff value of VA fundus diameter was set at 0.865 mm. Although <5% of the variability in the ABG was explainable by variation in the diameter of the VA fundus at low frequencies, on average, larger gaps were observed with fundus diameters of >0.865 mm. CONCLUSIONS: Our findings suggest that the axial parameters of the VA yield information about ABG in patients with EVA. The data are consistent with the hypothesis that an EVA introduces a third mobile window into the inner ear, resulting in an ABG at low frequencies.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/141835
DOI
10.1002/lary.25664
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Otorhinolaryngology
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
Yonsei Authors
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Link
 http://onlinelibrary.wiley.com/doi/10.1002/lary.25664/abstract
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