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Prognostic impact of preexisting hypertension and high systolic blood pressure at admission in patients hospitalized for systolic heart failure

Title
 Prognostic impact of preexisting hypertension and high systolic blood pressure at admission in patients hospitalized for systolic heart failure
Authors
 Ji Hyun Lee; Jun-Won Lee; Byung-Su Yoo; Kyu-Hyung Ryu; Dong-Ju Choi; Eun-Seok Jeon; Seok-Min Kang; Jaewon Oh; Junghan Yoon; Seung-Hwan Lee; Jang Young Kim; Sung Gyun Ahn; Min Soo Ahn; Young-Jin Youn
Issue Date
2015
Journal Title
 Journal of Cardiology
ISSN
 0914-5087
Citation
 Journal of Cardiology, Vol.null(null) : null, 2015
Abstract
BACKGROUND: Higher systolic blood pressure (SBP) has been reported to be associated with a better prognosis in heart failure (HF) patients. This study aimed to investigate the prognostic impact of hypertension in patients hospitalized with systolic HF. METHODS: Pooled analysis of data from three Korean observational studies was performed. Patients ≥18 years hospitalized with systolic HF (ejection fraction ≤45%) (n=3538) were compared for the incidence of 1-year all-cause mortality according to the presence of preexisting hypertension and SBP quartiles on admission. RESULTS: Patients with hypertension (prevalence, 51.6%) presented more often with diabetes (43.9% vs. 23.0%, p<0.001) and chronic kidney disease (14.1% vs. 5.7%, p<0.001). During the 1-year follow-up, patients with hypertension showed similar cumulative incidences of all-cause mortality as those without hypertension (8.3% vs. 8.4%, p=0.900). Conversely, patients with higher SBP on admission had a lower incidence of all-cause death (quartile 4 vs. 1: 6.7% vs. 11.3%, p for trend=0.004). In the multivariate analysis, an increase in SBP of 10mmHg was associated with an 8.5% risk reduction of all-cause death (hazard ratio: 0.915, 95% confidence interval: 0.853-0.981, p=0.013). CONCLUSIONS: Higher SBP on admission was independently associated with a lower risk of 1-year all-cause mortality in systolic HF.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/141827
DOI
10.1016/j.jjcc.2015.08.005
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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Link
 http://www.sciencedirect.com/science/article/pii/S0914508715002439
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