Cited 0 times in

Role of transcription factor acetylation in the regulation of metabolic homeostasis

Title
Role of transcription factor acetylation in the regulation of metabolic homeostasis
Authors
Joo-Man Park;Seong-Ho Jo;Yong-Ho Ahn;Tae-Hyun Kim;Mi-Young Kim
Issue Date
2015
Journal Title
Protein & Cell
ISSN
1674-800X
Citation
Protein & Cell, Vol.6(11) : 804~813, 2015
Abstract
Post-translational modifications (PTMs) of transcription factors play a crucial role in regulating metabolic homeostasis. These modifications include phosphorylation, methylation, acetylation, ubiquitination, SUMOylation, and O-GlcNAcylation. Recent studies have shed light on the importance of lysine acetylation at nonhistone proteins including transcription factors. Acetylation of transcription factors affects subcellular distribution, DNA affinity, stability, transcriptional activity, and current investigations are aiming to further expand our understanding of the role of lysine acetylation of transcription factors. In this review, we summarize recent studies that provide new insights into the role of protein lysine-acetylation in the transcriptional regulation of metabolic homeostasis.
URI

http://ir.ymlib.yonsei.ac.kr/handle/22282913/141771
DOI
10.1007/s13238-015-0204-y
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Biochemistry & Molecular Biology
Yonsei Authors
사서에게 알리기
  feedback
Files in This Item:
T201504333.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse