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Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features

Title
 Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features 
Authors
 Chae Jung Park ; Eun-Kyung Kim ; Min Jung Kim ; Jung Hyun Yoon ; Hee Jung Moon ; Ha Young Woo 
Issue Date
2015
Journal Title
 Journal of Breast Cancer 
ISSN
 1738-6756 
Citation
 Journal of Breast Cancer, Vol.18(3) : 291~295, 2015 
Abstract
Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/141607
DOI
10.4048/jbc.2015.18.3.291
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
Yonsei Authors
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