Cited 0 times in

Applying the bacterial meningitis score in children with cerebrospinal fluid pleocytosis: a single center's experience

Title
 Applying the bacterial meningitis score in children with cerebrospinal fluid pleocytosis: a single center's experience 
Authors
 Jungpyo Lee ; Hyeeun Kwon ; Hoon Chul Kang ; Heung Dong Kim ; Joon Soo Lee 
Issue Date
2015
Journal Title
 Korean Journal of Pediatrics 
ISSN
 1738-1061 
Citation
 Korean Journal of Pediatrics, Vol.58(7) : 251~255, 2015 
Abstract
PURPOSE: The widespread introduction of bacterial conjugate vaccines has decreased the risk of cerebrospinal fluid (CSF) pleocytosis due to bacterial meningitis (BM) in children. However, most patients with CSF pleocytosis are hospitalized and treated with parenteral antibiotics for several days. The bacterial meningitis score (BMS) is a validated multivariate model derived from a pediatric population in the postconjugate vaccine era and has been evaluated in several studies. In the present study, we examined the usefulness of BMS in South Korean patients. METHODS: This study included 1,063 patients with CSF pleocytosis aged between 2 months and 18 years. The BMS was calculated for all patients, and the sensitivity and negative predictive value (NPV) of the test were evaluated. RESULTS: Of 1,063 patients, 1,059 (99.6%) had aseptic meningitis (AM). Only four patients (0.4%) had BM. The majority of patients (98%) had a BMS of ≤1, indicating a diagnosis of AM. The BMS was 0 in 635 patients (60%) and 1 in 405 patients (38%). All four BM patients had a BMS of ≥4. CONCLUSION: To our knowledge, this is the first study to investigate the diagnostic strength of the BMS in South Korea. In our study, the BMS showed 100% sensitivity and 100% NPV. Therefore, we believe that the BMS is a good clinical prediction rule to identify children with CSF pleocytosis who are at a risk of BM.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/141546
DOI
10.3345/kjp.2015.58.7.251
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Pediatrics
Yonsei Authors
사서에게 알리기
  feedback
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse