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헬리코박터 파일로리(Helicobacter pylori) 감염 및 치료법 개요

Other Titles
 Overview of Helicobacter pylori and Treatment Options 
Authors
 송영구 
Citation
 Economic and Environmental Geology (자원환경지질), Vol.48(3) : 241 ~246, 2015 
Journal Title
 Economic and Environmental Geology (자원환경지질) 
ISSN
 1225-7281 
Issue Date
2015
Abstract
Helicobacter pylori is an important transmissible human pathogen found on the luminal surface of the gastric epithelium. The organism can persist in the stomach indefinitely and causes gastroduodenal inflammation that may proceed to atrophic gastritis, peptic ulcer, gastric MALT lymphoma, and gastric cancer. Standard triple therapy which consists of proton pump inhibitor (PPI) plus two antibiotics (amoxicillin and clarithromycin) is now generally used in Korea, however, eradication rates of H. pylori has been decreasing due to increasing antibiotic resistance. In this review, current second-line treatment regimens, difficult problems on treatment, necessity of local target therapy, applicability of clay minerals as a drug delivery system (DDS), and a new therapeutic strategy and its study plans will be discussed.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/140937
DOI
10.9719/EEG.2015.48.3.241
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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