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Usefulness of the controlled attenuation parameter for detecting liver steatosis in health checkup examinees

Title
 Usefulness of the controlled attenuation parameter for detecting liver steatosis in health checkup examinees 
Authors
 Ja Kyung Kim ; Kwan Sik Lee ; Jung Il Lee ; Kyung Ah Lee ; Da Hyun Jung ; Hyun Jung Chung ; Jung Ran Choi 
Issue Date
2015
Journal Title
 Gut and Liver 
ISSN
 1976-2283 
Citation
 Gut and Liver, Vol.9(3) : 405~410, 2015 
Abstract
BACKGROUND/AIMS: The controlled attenuation parameter (CAP) implemented in FibroScan® is reported to be a noninvasive means of detecting steatosis (>10% steatosis). We aimed to evaluate the usefulness of CAP in detecting steatosis among health checkup examinees and to assess its correlation with ultrasonography (US). METHODS: Consecutive CAP results were retrospectively collected. A total of 280 subjects were included. RESULTS: Fatty liver was detected in 119 subjects (42.5%) by US, whereas it was detected in 160 subjects (57.1%) by the CAP. The numbers of subjects with S0S1S2S3 steatosis according to the CAP value were 120595843, respectively. The mean CAP values were 203.34±28.39 dB/m for S0, 248.83±6.14 dB/m for S1, 274.33±8.53 dB/m for S2, and 322.35±22.20 dB/m for S3. CAP values were correlated with body weight (r=0.404, p<0.001), body mass index (r=0.445, p<0.001), and the fatty liver grade by US (r=0.472, p<0.001). Among the 161 subjects with normal US findings, steatosis was detected in 65 subjects (40.4%) using the CAP. CONCLUSIONS: The CAP seems to be useful for detecting very low-grade hepatic steatosis in health checkup examinees. Its role in predicting subjects with a risk of metabolic derangement needs to be evaluated.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/140863
DOI
10.5009/gnl14202
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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