Cited 26 times in
The Role of Orexin in Post- Stroke; Emphasizing on Inflammation, Cognitive decline, Depression following Stroke.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김어수 | - |
dc.contributor.author | 김철훈 | - |
dc.contributor.author | 송주현 | - |
dc.contributor.author | 송호택 | - |
dc.contributor.author | 이종은 | - |
dc.date.accessioned | 2016-02-04T11:04:18Z | - |
dc.date.available | 2016-02-04T11:04:18Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/139599 | - |
dc.description.abstract | Ischemic stroke results in diverse pathophysiologies, including cerebral inflammation, neuronal loss, cognitive dysfunction, and depression. Studies aimed at identifying therapeutic solutions to alleviate these outcomes are important due to the increase in the number of stroke patients annually. Recently, many studies have reported that orexin, commonly known as a neuropeptide regulator of sleep/wakefulness and appetite, is associated with neuronal cell apoptosis, memory function, and depressive symptoms. Here, we briefly summarize recent studies regarding the role and future perspectives of orexin in post-ischemic stroke. This review advances our understanding of the role of orexin in post-stroke pathologies, focusing on its possible function as a therapeutic regulator in the post-ischemic brain. Ultimately, we suggest the clinical potential of orexin to regulate post-stroke pathologies. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | MOLECULAR BRAIN | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Cognition Disorders/etiology* | - |
dc.subject.MESH | Cognition Disorders/metabolism | - |
dc.subject.MESH | Depression/etiology* | - |
dc.subject.MESH | Depression/metabolism | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Inflammation/etiology* | - |
dc.subject.MESH | Inflammation/metabolism | - |
dc.subject.MESH | Models, Biological | - |
dc.subject.MESH | Orexins/metabolism* | - |
dc.subject.MESH | Stroke/complications* | - |
dc.subject.MESH | Stroke/metabolism | - |
dc.title | The Role of Orexin in Post- Stroke; Emphasizing on Inflammation, Cognitive decline, Depression following Stroke. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Juhyun Song | - |
dc.contributor.googleauthor | Eosu Kim | - |
dc.contributor.googleauthor | Chul-Hoon Kim | - |
dc.contributor.googleauthor | Ho-Taek Song | - |
dc.contributor.googleauthor | Jong Eun Lee | - |
dc.identifier.doi | 10.1186/s13041-015-0106-1 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00686 | - |
dc.contributor.localId | A01057 | - |
dc.contributor.localId | A02063 | - |
dc.contributor.localId | A02080 | - |
dc.contributor.localId | A03146 | - |
dc.relation.journalcode | J02251 | - |
dc.identifier.eissn | 1756-6606 | - |
dc.identifier.pmid | 25884812 | - |
dc.subject.keyword | Post-stroke | - |
dc.subject.keyword | Orexin | - |
dc.subject.keyword | Inflammation | - |
dc.subject.keyword | Cognitive dysfunction | - |
dc.subject.keyword | Depression | - |
dc.contributor.alternativeName | Kim, Eo Su | - |
dc.contributor.alternativeName | Kim, Chul Hoon | - |
dc.contributor.alternativeName | Song, Ju Hyun | - |
dc.contributor.alternativeName | Song, Ho Taek | - |
dc.contributor.alternativeName | Lee, Jong Eun | - |
dc.contributor.affiliatedAuthor | Kim, Eo Su | - |
dc.contributor.affiliatedAuthor | Kim, Chul Hoon | - |
dc.contributor.affiliatedAuthor | Song, Ju Hyun | - |
dc.contributor.affiliatedAuthor | Song, Ho Taek | - |
dc.contributor.affiliatedAuthor | Lee, Jong Eun | - |
dc.rights.accessRights | not available | - |
dc.citation.volume | 8 | - |
dc.citation.startPage | 16 | - |
dc.identifier.bibliographicCitation | MOLECULAR BRAIN, Vol.8 : 16, 2015 | - |
dc.identifier.rimsid | 52353 | - |
dc.type.rims | ART | - |
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