건강한 성인에서의 규칙적인 운동량과 백혈구 수와의 연관성

Abstract

[한글]

본 연구는 1998년 11월 1일부터 12월 31일까지 실시되었던 「국민건강·영양조사」중 건강검진조사자료를 이용하여 현재 규칙적인 운동군과 비운동군의 백혈구 수의 수준을 비교하고 이에 영향을 미치는 요인을 파악하고자 「국민건강·영양조사」에서 조사된 13,421명중 ''보건의식행태조사''와 ''건강검진조사''를 받은 20세 이상 성인 9,764명의 자료를 이용하였고 고혈압등 유 질환자들을 제외한 5,311명을 연구대상으로 하였다.

첫째, 정기적으로 운동을 하는 운동군은 927명(남: 479, 여: 448)이었고, 비운동군은 4,384명(남: 1756, 여: 2628)이었으며, 운동군에서의 백혈구 수는 5732.5±1486.5/ul, Hct은 41.9±4.7%, MCHC는 33.6 / ±0.8g/dL, 혈소판은 23.6±5.2x1010/L이었고, 비운동군에서의 백혈구 수는 5831.2±1473.4/ul, Hct은 40.9±4.7%, MCHC는 33.7 / ±1.0g/dL, 혈소판은 23.9±5.41010/L으로 나타났다.

둘째, 운동량이 많은 군이 비운동군에 비해 여성에서 평균 백혈구 수가 더 적은 것으로 나타났다.

셋째, 다른 변수를 통제하였을 때 비운동군보다 운동량이 많은 군이 백혈구 수가 더 적은 것으로 나타났다.

이상의 연구결과를 종합해 볼 때, 운동여부 그리고 운동량과 백혈구 수는 관련이 있었다.

[영문]

The purpose of this study is to compare White Blood Cell (WBC) count level as a marker of inflammation between no regular exercise group and regular exercise group, and to investigate the factors that associated with WBC count level.

It has been well known that regular physical exercise has been associated with a reduced risk of coronary heart disease; however, the mechanism underlying such association is unclear. Coronary heart disease is increasingly seen as an inflammatory process; therefore, it might be reasonable to hypothesize that physical activity reduces risk of coronary heart disease by reducing or preventing White Blood Cell counts as a marker of inflammation.

This study is based on the health check-up data collected from National Health and Nutrition Investigation Report」in 1998. From the total sample of 13,421, 9,764 adults over 20 years old, who participated in the ''Public Health Awareness Report'' and ''Health Check-up'', were chosen as the study sample. Furthermore, the sample was carefully chosen by excluding the people with Hypertension, Diabetes, Rheumatoid arthritis, Asthma, Bronchitis, Emphysema, all kinds of cancer, Heart failure, Coronary artery disease, Myocardial infarction,

Cataract, Sinusitis, Chronic Otitis Media, Glaucoma.

A total number of 5,311 subjects has been analyzed thoroughly by this study. Among those, 4,384 were Non-regular exercise group and 927 were Regular exercise group. We studied the relationship between WBC counts and presence of regular physical exercise and total weekly energy expenditure by multiple regression analysis excluding confounding variables.

The following is the results from this study:

1. Among 5311 subjects, 927(13.5%) subjects was engaged in regular exercise(Exercise group) and 4,384(82.5%) subjects(Non-exercise group) were not. There were differences in the means of WBC count and other hematologic findings(Hematocrit, platelet) between groups. The Mean WBC counts , Hct(%), MCHC, Platelet count in regular exercise group were 5732.5±1486.5/ul, 41.9±4.7%, 33.6±/ 0.8g/dL, 23.6±5.2x1010/L. In non-exercise group, 5831.2±1473.4/ul, / 40.9±4.7%, 33.7±1.0g/dL, 23.9±5.4x1010/L were noticed.

2. The mean WBC count in the high regular physical exercise group was lower than Non-exercise group and low physical activity group in women.

3. High regular physical exercise is independently associated with a lower WBC count levels among apprently healthy KOREA adults, independently of several confounding factors.

In summarizing the result of this study, the high regular physical

activity is related with lowered White Blood Cell counts regardless of

other confounding factors.