Bacteriological study of endogenous pyogenic infection in orthopedic field
233 cases of endogenous pyogenic osteomyelitis, arthritis, myositis were studied. The 233 cases included: 167 cases of osteomyelitis, 32 cases of arthritis and 34 cases of myositis.
268 different strains were found which belonged to 8 bacterial genera. The etiological agents were as follows: staphylococci 70%, coliform bacilli 12%, Gram(+) cocci 6%, streptococci 5%, pseudomonas 4%, proteus 3%, salmonella 1%, Gram(-) coccobacilli 0.4%.
The single disk method for bacteriological antibiotic sensitivity test provided the data upon which this report is based.
The results are summarized as follows:
1. The most common bacteriae, staphylococci were most sensitive to albamycin(91%) and also sensitive to leucomycin, erythromycin, tetracycline, kanamycin, ampicillin and cloxacillin. They were highly resistant to penicillin, streptomycin and neomycin. There was a trend of increased sensitivity to pennicillin and chloramphenicol but decreased sensitivity to neomycin.
2. Streptococci were sensitive to leucomycin, albamycin, erythromycin but highly resistant to penicillin, streptomycin, tetracycline, neomycin and kanamycin.
3. Cliform bacilli were highly resistant to all antibiotics used in this study except kanamycin(72%).
4. Pseudomonas was highly resistant to the various antibiotics tested and was only slightly sensitive to tetracycline.
5. Proteus was sensitive to streptomycin and kanamycin but resistant to other antibiotics.
6. In sensitivity to each antibiotics, all organisms were highly sensitive to albamycin, kanamycin, ampicillin, and cloxacillin. There was a trend of increased sensitivity to penicillin and chloramphenicol.
At present, before the sensitivity test report is available, albamycin, kanamycin, ampicillin and cloxacillin should be used, penicillin, streptomycin and neomycin should not be used.