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성견의 실험적 상피하 결합조직 이식시의 치주조직의 치유

Other Titles
 Periodontal wound healing of the experimental subepithelial connective tissue graft in dogs 
Authors
 정현철 
Issue Date
1997
Description
치의학과/석사
Abstract
[한글]

치주질환에 의해 파괴된 치주조직의 재생이나 기능회복을 위해 여러 가지 술식들이 이용되어져 왔다. 그중 치은퇴축의 심미적 문제가 있거나, 노출된 치근면의 피개가 필요시 이의 회복을 위해 치조점막수술중 하나인 상피하 결합조직이식술이 사용되고 있다.

본 연구의 목적은 치근면에 상피하 결합조직이식시 치주조직의 치유과정과 이에 따른 접합상피와 결합조직의 재생과 부착정도 등 전반적인 재생과 재부착에 미치는 영향을 평가하기 위함이다. 이를위해 5마리의 성견의 전치 협면부위에 치조골이 백악-법랑경계와

치아장축으로부터 치조골변연까지 4×3mm 깊이4mm,넓이3mm) 치조골을 제거한후, 치근활택술만 시행하고 판막을 봉합한 경우를 대조군으로, 치근활택술후 상피하 결합조직이식술을 시행한 경우를 실험군으로하여, 각 2일, 4일, 1주, 2주, 4주후의 조직학적 소견과 그

치유과정을 관찰하여 다음과 같은 결과를 얻었다.

1. 혈병은 두 군에서 실험초기 2, 4일에 관찰되었으며, 1주후 흡수되었다.

2. 염증상태는 두 군에서 초기 2, 4일에는 중증도의 염증상태를 보였고, 1주, 2주에 현격히 감소하였으며, 4주에는 소실되었다.

3. 접합상피의 근단이동은 대조군에서 심했으나, 실험군에서는 이식편에 의해 접합상피의 근단이동이 억제됨을 볼 수 있었다.

4. 결합조직의 치근과의 배열양상은 두 군에서 2주부터 부분적으로 수평배열을 보였고, 4주후부터 전반적인 수평배열을 보였다.

5. 실험군에서의 이식편의 문합은 4일부터 관찰되어 4주후에는 인접치은 결합조직과의 경계를 구별할 수 없었다.

[영문]

Several methods have been used for regeneration of tissue lost by periodontal disease. Subepithelial connective tissue graft technique, one of the technniques of mucogingival surgery, is used for the regeneration in esthetic problems such as recession, and denuded root coverage.

This study is performed to evaluate the healing process and the regeneration and reattachment of periodontal tissue, including the reconstruction of junctional epithelium, and connective tissue.

Alveolar defects in five adult dogs were treated with periodontal surgery and were attained by removing the marginal alveolar bone by 4×3mm from CEJ in the labial side of incisors, and root surfaces were planed.

The experimental sites were divided into two groups as follows.

1. root planing alone (control group) 2. with connective tissue graft (Experimental Group)

In the two groups flaps were positioned and sutured tightly, the healing processes were observed and were histologically compared with each other after 2days, 4days, 1week, 2weeks, 4weeks.

The results were obtained as follows :

1. In the two groups blood clots were observed as early as 2 and 4 days, and were resorbed at 1 week.

2. In the two groups moderate inflammation was observed as early as 2 and4 days, decreased at 1 and 2 weeks, and disappeared at 4 weeks.

3. Junctional Epithelium migration was more significant in the control group, and was restrained by graft materials in the experimental group.

4. Features of connective tissue fiber attachment partially showed the parallel pattern in the two groups from 2 weeks, and entirely from 4weeks.

5. Anastomosis, between graft and connective tissue, appeared from 4 days in the experimental group and the border between them was not discriminated at 4weeks.
Full Text
https://ymlib.yonsei.ac.kr/catalog/search/book-detail/?cid=CAT000000005763
Files in This Item:
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Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Advanced General Dentistry (통합치의학과) > 2. Thesis
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/125513
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